| Type | Description |
|---|---|
| Definition | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:23:00 | The YAP/SERCA2a signaling pathway protects cardiomyocytes against reperfusion-induced apoptosis. | 32645692 |
| 2021-01-23 13:00:00 | Inactivation of cysteine 674 in the SERCA2 accelerates experimental aortic aneurysm. | 32035136 |
| 2020-12-19 13:40:00 | Conditional Up-Regulation of SERCA2a Exacerbates RyR2-Dependent Ventricular and Atrial Arrhythmias. | 32260593 |
| 2020-07-25 10:57:00 | The DMF-elicited current had the electrophysiological characteristics of a transient receptor potential channel and the intracellular calcium levels were normalized by antagonists of TRPA1. Interestingly, the sarco/endoplasmic reticulum Ca(2+)-ATPase SERCA2b was downregulated but more active due to glutathionylation of the redox-sensitive cysteine 674. | 31279969 |
| 2020-04-04 12:58:00 | These results directly link transcriptional control of SERCA2 activity, depressed sarcoplasmic reticulum Ca(2+) sequestration, enhanced trans-sarcolemmal calcium fluxes, and atrial fibrillation, establishing a mechanism underlying the genetic basis for a Ca(2+)-dependent pathway for atrial fibrillation risk in Tbx5-deficient mice. | 30896405 |
| Type | IDs |
|---|---|
| Synonymous | 9530097L16Rik, D5Wsu150e, SERCA2, SERCA2B, Serca2a, mKIAA4195 |
| Gene |
UniProtKB-ID:
AT2A2_MOUSE,
Q5DTI2_MOUSE
UniprotKB:
O55143,
Q5DTI2
UniParc:
UPI0000027AE6,
UPI00004E1788,
UPI0000027FD7
EMBL:
AJ131821,
AK220538,
BC054531,
AJ131870,
AF029982,
BC054748,
AJ223584
Ensembl:
ENSMUSG00000029467
KO:
mmu:11938
|
| Nucleutide sequences |
EMBL-CDS:
CAB41018.1,
AAH54531.1,
AAD01889.1,
CAA11450.1,
CAB72436.1,
AAH54748.1,
CAB41017.1,
BAD90532.1
Ensembl_TRS:
ENSMUST00000179939,
ENSMUST00000177974,
ENSMUST00000031423
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000135935,
ENSMUSP00000031423,
ENSMUSP00000136104
RefSeq:
NP_033852.1,
NP_001103610.1
|
| Others |
UniRef100:
UniRef100_O55143
UniRef90:
UniRef90_O55143
UniRef50:
UniRef50_P16615
UniGene:
Mm.227583
CCDS:
CCDS57378.1,
CCDS57379.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员