| Type | Description |
|---|---|
| Definition | antioxidant 1 copper chaperone |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:34:00 | Cu-dependent Atox1 binding to TRAF4 plays an important role in Atox1 nuclear translocation and inflammatory responses in TNF-alpha-stimulated vascular endothelial cells. | 31553645 |
| 2019-04-06 11:12:00 | Transduced Tat-ATOX1 markedly suppressed inflammatory responses in LPS-exposed Raw 264.7 cells and in a TPA-induced animal model by inhibition of pro-inflammatory mediator proteins, as well as activated NF-B and MAPK, suggesting that Tat-ATOX1 may contribute to the development of therapeutic proteins for the treatment of skin inflammation. | 30545441 |
| 2017-08-26 11:14:00 | ATOX1 appeared ubiquitously expressed throughout the cells until compaction; in subsequent embryo stages, ATOX1 relocalized to cytoplasmic perinuclear domains in the inner cell mass. Silencing of Oct4 did not affect Atox1 expression, but silencing of Atox1 at the 2-cell stage strongly diminished Oct4 expression in 16-cell embryos. | 28711491 |
| 2016-08-13 11:45:00 | Cu chaperone function of Atox1 mediated through Cu transporter ATP7A is required for VEGF-induced angiogenesis via activation of Cu enzyme lysyl oxidase. | 26437801 |
| 2013-05-04 11:35:00 | Atox1 is involved in neointimal formation after vascular injury through promoting vascular smooth muscle cell migration and inflammatory cell recruitment in injured vessels | 23349186 |
| Type | IDs |
|---|---|
| Synonymous | AI256639, Atx1 |
| Gene |
UniProtKB-ID:
ATOX1_MOUSE
UniprotKB:
O08997
UniParc:
UPI0000001A47
EMBL:
AF004591,
AL596207,
BC027632,
AK002432
Ensembl:
ENSMUSG00000018585
KO:
mmu:11927
|
| Nucleutide sequences |
EMBL-CDS:
AAB61465.1,
BAB22098.1,
AAH27632.1
Ensembl_TRS:
ENSMUST00000108857
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104485
RefSeq:
NP_033850.1
|
| Others |
UniRef100:
UniRef100_O08997
UniRef90:
UniRef90_Q9WUC4
UniRef50:
UniRef50_Q9WUC4
UniGene:
Mm.217759
CCDS:
CCDS36158.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员