| Type | Description |
|---|---|
| Definition | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:30:00 | Tumor size and the number of diethylnitrosamine and carbon tetrachloride-induced liver tumors significantly increased in antithrombin (AT)-insufficient mice compared with the wild-type mice. AT insufficiency led to increased susceptibility to liver tumorigenesis by increasing hepatic inflammation. | 30694755 |
| 2019-03-30 11:29:00 | Trancriptomic analysis shows that expression of the antithrombins serpin C1 and D1 is significantly reduced in Schwann cell-deficient mice. In the absence of peripheral neuromuscular activity, neurodegeneration is completely blocked, and expression of prothrombin in muscle is markedly reduced. | 30870413 |
| 2013-07-27 10:44:00 | RNA interference of Serpinc1 and/or Proc allows for evaluation of the function of these genes in vivo and provides a novel, controlled mouse model for spontaneous venous thrombosis. | 23550037 |
| 2010-01-21 00:00:00 | in the heart, TF plays an important role in the thrombogenesis and it counterbalances AT-dependent anticoagulation; regulation of TF-procoagulant activity take place differently between the liver and the heart | 16409467 |
| 2010-01-21 00:00:00 | Mice homozygous for the heparin-binding domain mutation R48C developed spontaneous, life-threatening thrombosis, occurring as early as the day of birth. Only 60% of the offspring reached weaning age, with further loss at different ages | 14592998 |
| Type | IDs |
|---|---|
| Synonymous | AI114908, ATIII, At-3, At3 |
| Gene |
UniProtKB-ID:
ANT3_MOUSE,
Q543J5_MOUSE
UniprotKB:
P32261,
Q543J5
UniParc:
UPI0000000900
EMBL:
S47225,
AB043785,
AK050295,
BC033377,
BC019447
Ensembl:
ENSMUSG00000026715
KO:
mmu:11905
|
| Nucleutide sequences |
EMBL-CDS:
AAH19447.1,
AAB23965.1,
AAH33377.1,
BAB16827.1,
BAC34171.1
Ensembl_TRS:
ENSMUST00000064725
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068971
RefSeq:
XP_030099556.1,
XP_006496689.1,
NP_543120.1,
NP_001366231.1
|
| Others |
UniRef100:
UniRef100_P32261
UniRef90:
UniRef90_P32261
UniRef50:
UniRef50_P01008
UniGene:
Mm.260770
CCDS:
CCDS15411.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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