| Type | Description |
|---|---|
| Definition | N-acylsphingosine amidohydrolase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:25:00 | Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice. | 32015399 |
| 2020-08-01 11:54:00 | Lack of aCDase in macrophage cultures or in Asah1(-/-) mice results in replication of HSV-1 and Asah1(-/-) mice die soon after systemic or intravaginal inoculation. | 32165633 |
| 2020-06-27 12:29:00 | Although no significant morphologic changes in glomeruli were observed in these podocyte-specific knockout mice, severe proteinuria and albuminuria were found compared with control littermates. TEM analysis showed that podocytes of the knockout mice had distinctive foot process effacement and microvillus formation. | 32194052 |
| 2020-02-29 11:06:00 | Endothelium-specific acid ceramidase (AC) gene knockout mice (Asah1(fl/fl)/EC(cre)) significantly enhanced the formation and activation of NLRP3 inflammasomes in coronary arterial endothelial cells. | 31647995 |
| 2019-10-26 11:02:00 | Asah1(P361R/P361R) mice exhibit progressive retinal and optic nerve pathology. Through noninvasive ocular imaging and histopathological analyses of these Asah1(P361R/P361R) animals, we revealed progressive inflammation, the presence of retinal dysplasia, and significant storage pathology in various cell types in both the retina and optic nerves. | 30472209 |
| Type | IDs |
|---|---|
| Synonymous | 2310081N20Rik, AC, Asah |
| Gene |
UniProtKB-ID:
ASAH1_MOUSE,
Q78P93_MOUSE
UniprotKB:
Q9WV54,
Q78P93
UniParc:
UPI0000000AB0
EMBL:
AK075919,
AK075666,
AK077721,
BC003204,
AY028080,
AK151478,
AF352179,
AK166757,
AK090314,
AF157500
Ensembl:
ENSMUSG00000031591
KO:
mmu:11886
|
| Nucleutide sequences |
EMBL-CDS:
BAC35884.1,
AAD39551.1,
AAH03204.1,
BAC41166.1,
BAE30433.1,
BAC36980.1,
BAC36053.1,
AAK39512.1,
AAK21979.1,
BAE38998.1
Ensembl_TRS:
ENSMUST00000034000
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034000
RefSeq:
XP_017168024.1,
XP_017168025.1,
NP_062708.1,
XP_017168016.1,
XP_030099113.1,
XP_017168021.1,
XP_017168023.1,
XP_017168019.1,
XP_017168020.1,
XP_017168017.1,
XP_036009623.1,
XP_017168022.1
|
| Others |
UniRef100:
UniRef100_Q9WV54
UniRef90:
UniRef90_Q9WV54
UniRef50:
UniRef50_Q9WV54
UniGene:
Mm.22547
CCDS:
CCDS22262.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员