Type | Description |
---|---|
Definition | chloride voltage-gated channel Ka |
Date | Results | Publications |
---|---|---|
2020-12-26 13:12:00 | Role of in the Regulation of the Human Kidney Chloride Channel ClC-Ka. | 32581267 |
2019-01-19 10:43:00 | Increasing expression of barttin over that of ClC-K partially recovered this insufficiency, indicating that N-terminal modifications of barttin alter both binding affinities and gating properties | 29674316 |
2016-08-27 12:45:00 | Single loci of tag of CLCNKA_B are not enough to increase the Essential Hypertension susceptibility, the combination of CLCNKA SNP, salt, marine products, meat, edible oil consumption is associated with elevated risk. | 25919862 |
2015-10-03 10:44:00 | R8W and G47R, two naturally occurring barttin mutations identified in patients with Bartter syndrome type IV, reduce barttin palmitoylation and CLC-K/barttin channel activity. | 26013830 |
2014-10-04 10:06:00 | HEK293 cells the potentiating effect of niflumic acid (NFA) on CLC-Ka/barttin and CLC-Kb/barttin channels seems to be absent while the blocking efficacy of niflumic acid and benzofuran derivatives observed in oocytes is preserved | 24863058 |
Type | IDs |
---|---|
Synonymous | CLCK1, ClC-K1, hClC-Ka |
Gene |
UniProtKB-ID:
CLCKA_HUMAN
UniprotKB:
P51800
UniParc:
UPI0001AE77E5,
UPI0000127993,
UPI0000205CC5
EMBL:
AL355994,
BC053869,
Z30643,
U93878,
BC048282,
AK225550,
AK298285
Ensembl:
ENSG00000186510
KO:
hsa:1187
|
Nucleutide sequences |
EMBL-CDS:
AAH48282.1,
CAA83120.1,
AAH53869.1,
AAB65148.1,
BAG60545.1
Ensembl_TRS:
ENST00000331433,
ENST00000439316,
ENST00000375692
|
Protein sequencees |
Ensembl_PRO:
ENSP00000332771,
ENSP00000364844,
ENSP00000414445
RefSeq:
NP_001244068.1,
NP_001036169.1,
NP_004061.3
|
Others |
UniRef100:
UniRef100_P51800
UniRef90:
UniRef90_P51800
UniRef50:
UniRef50_P51800
UniGene:
Hs.591533
CCDS:
CCDS167.1,
CCDS41269.1,
CCDS57973.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员