| Type | Description |
|---|---|
| Definition | aryl hydrocarbon receptor nuclear translocator 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-16 10:34:00 | In the absence of synaptic excitation, ARNT2 recruits the NCoR2 co-repressor complex to suppress neuronal activity-dependent regulatory elements and maintain low basal levels of inducible genes. in response to heightened neuronal activity, ARNT2 recruits NPAS4 to activity-dependent regulatory elements to induce transcription and thereby increase somatic inhibitory input. | 30846309 |
| 2019-06-22 10:30:00 | These findings establish a requirement for ARNT2-dependent genes in the maintenance of the homeostatic feeding response, necessary for prevention of obesity and obesity-related diseases. | 30563851 |
| 2018-12-22 11:55:00 | The data of this study support ARNT2 as a neuronal transcription factor whose sustained expression is linked to neuronal and axonal health, protection that may primarily be driven through its partnering with Npas4 to influence BDNF expression. | 30231889 |
| 2010-01-21 00:00:00 | The differential binding of AhR by Arnt and Arnt2 can be ascribed to a single His/Pro amino acid difference in the PASB region of Arnt and Arnt2. | 17023418 |
| 2010-01-21 00:00:00 | data suggest that ARNT2/HIF-2beta is required at high levels during nephrogenesis in distal tubules and later exclusively in thick ascending limb | 15466261 |
| Type | IDs |
|---|---|
| Synonymous | Hif-2b, bHLHe1, mKIAA0307 |
| Gene |
UniProtKB-ID:
ARNT2_MOUSE
UniprotKB:
Q61324
UniParc:
UPI0000192A15,
UPI00001F5A7A
EMBL:
AB093225,
BC054546,
D63644
Ensembl:
ENSMUSG00000015709
KO:
mmu:11864
|
| Nucleutide sequences |
EMBL-CDS:
BAC41409.1,
BAA09799.1,
AAH54546.1
Ensembl_TRS:
ENSMUST00000085077,
ENSMUST00000208232,
ENSMUST00000209133
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000147129,
ENSMUSP00000082154,
ENSMUSP00000146413
RefSeq:
NP_031514.3,
XP_036008493.1,
XP_036008495.1,
XP_006507301.1,
XP_030097877.1,
XP_006507305.1,
XP_006507307.1,
XP_036008496.1,
XP_006507306.1,
XP_006507302.1,
XP_036008494.1,
XP_011239957.1
|
| Others |
UniRef100:
UniRef100_Q61324
UniRef90:
UniRef90_Q61324
UniRef50:
UniRef50_P27540-4
UniGene:
Mm.38594
CCDS:
CCDS59733.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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