| Type | Description |
|---|---|
| Definition | glypican 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-20 10:35:00 | The results suggest that Gpc4 is crucial for generating the environment required for efficient migration of endodermal cells, uncovering a novel function of Gpc4 during development. | 30082271 |
| 2017-09-09 14:29:00 | the chaperon Wls and its ligands Wnt9a and Wnt5b are expressed in the ectoderm, whereas juxtaposed chondrocytes express Frzb and Gpc4. | 27287801 |
| 2017-08-19 12:36:00 | A mutation in glypican4 leads to severe lateral line primordium migration defects. Glypican4 regulates the feedback loop between Wnt/beta-catenin/Fgf signaling in the primordium redundantly with other HSPGs. A mutation in glypican4 affects primordium migration non cell-autonomously | 27640326 |
| 2017-06-10 10:12:00 | disruption of wls resulted in a significant loss of craniofacial bone, whereas lack of gpc4, wnt5b and wnt9a resulted in severely delayed endochondral ossification. | 27908786 |
| 2016-09-24 10:09:00 | novel mechanism for Wnt5b and Gpc4 regulation of chondrocyte behavior that is independent of the core Wnt/PCP molecules and differs from their collaborative action of controlling cell movements during gastrulation | 26459057 |
| Type | IDs |
|---|---|
| Synonymous | chunp6920, fc47a08, fe05f10, gpc4,, gpc4/6, gpc6, kny, knypek, wu:fc47a08, wu:fe05f10, zgc:194854 |
| Gene |
UniProtKB-ID:
B3DJ94_DANRE
UniprotKB:
B3DJ94
UniParc:
UPI00017661E6
EMBL:
BC163403
KO:
dre:118437
|
| Nucleutide sequences |
EMBL-CDS:
AAI63403.1
|
| Protein sequencees |
RefSeq:
NP_571935.2
|
| Others |
UniRef100:
UniRef100_B3DJ94
UniRef90:
UniRef90_Q90Z52
UniRef50:
UniRef50_O75487
UniGene:
Dr.78935
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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