| Type | Description |
|---|---|
| Definition | ADP-ribosylation factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:09:00 | ARF4(+/-)/ARF5(-/-) mice exhibited essential tremor (ET)-like behaviors and abnormal brain acitivity when moving. The decreased expression of the class II ARF proteins in ARF4(+/-)/ARF5(-/-) mice leads to a haploinsufficiency of ARF4 in the absence of ARF5 and impairs the localization of Nav1.6 to the AIS and hence reduces the membrane excitability in PCs, resulting in the ET-like movement disorder. | 31201232 |
| 2017-09-30 11:13:00 | Data suggest that, when compared to intestinal epithelial cells (IECs) from germ-free mice, IECs from mice with commensal bacteria exhibit increased expression of microRNA-21-5p; up-regulation of expression of microRNA-21-5p appears to increase IEC permeability and up-regulates ADP ribosylation factor 4 (Arf4/ARF4) in mouse and human cells. | 28760826 |
| 2017-06-03 11:36:00 | ARF4 is required for Presenilin basal body localization, Notch signaling, and subsequent epidermal differentiation. | 27354375 |
| 2017-06-03 11:27:00 | These findings are consistent with Arf4 playing a critical role in endomembrane trafficking, particularly in the pancreas, but not in ciliary function. | 28410364 |
| 2014-12-20 12:52:00 | This work suggests that while Arf4 is not required for ciliary assembly, it is important for the efficient transport of fibrocystin to cilia, and also plays critical roles in non-ciliary processes | 24586199 |
| Type | IDs |
|---|---|
| Synonymous | AA407803 |
| Gene |
UniProtKB-ID:
ARF4_MOUSE,
Q14BR4_MOUSE
UniprotKB:
P61750,
Q14BR4
UniParc:
UPI0000004154
EMBL:
BC115650,
AK081686,
AK013892,
AK153011,
BC115651,
D87901,
AK168793
Ensembl:
ENSMUSG00000021877,
ENSMUSG00000115861
KO:
mmu:11843
|
| Nucleutide sequences |
EMBL-CDS:
BAA13493.1,
BAE40626.1,
BAE31650.1,
BAB29041.1,
BAC38292.1,
AAI15651.1,
AAI15652.1
Ensembl_TRS:
ENSMUST00000022429,
ENSMUST00000230068
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022429,
ENSMUSP00000155713
RefSeq:
NP_031505.1
|
| Others |
UniRef100:
UniRef100_P61750
UniRef90:
UniRef90_P18085
UniRef50:
UniRef50_P18085
UniGene:
Mm.297768
CCDS:
CCDS26881.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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