| Type | Description |
|---|---|
| Definition | chloride voltage-gated channel 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:10:00 | Multicenter study of the clinical features and mutation gene spectrum of Chinese children with Dent disease. | 31674016 |
| 2020-10-24 13:59:00 | Cl(-) and H(+) coupling properties and subcellular localizations of wildtype and disease-associated variants of the voltage-gated Cl(-)/H(+) exchanger ClC-5. | 31852738 |
| 2019-10-19 12:32:00 | ClC-5 upregulation ameliorates renal fibrosis via inhibiting NF-kappaB/MMP-9 pathway signaling activation, suggesting that ClC-5 may be a novel therapeutic target for treating renal fibrosis and chronic kidney disease. | 31054069 |
| 2019-07-06 10:30:00 | ittle, if any, active H(+) transport, supported by ATP, occurred. Major transporters include cariporide-sensitive NHE1 in basolateral membranes and ClC3 and ClC5 in apical osteoblast membranes. The mineralization inhibitor levamisole reduced bone formation and expression of alkaline phosphatase, NHE1, and ClC5. | 30044661 |
| 2019-01-19 11:34:00 | Low CLC5 expression is associated with chemoresistance in Multiple Myeloma. | 28899456 |
| Type | IDs |
|---|---|
| Synonymous | CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2 |
| Gene |
UniProtKB-ID:
CLCN5_HUMAN,
V9GYG7_HUMAN,
A8K4H5_HUMAN,
B3KRR2_HUMAN
UniprotKB:
P51795,
V9GYG7,
A8K4H5,
B3KRR2
UniParc:
UPI00015DA613,
UPI0000127A9B,
UPI0000E0C4B9,
UPI000178DFF8,
UPI0000212052
EMBL:
BC130429,
BC130431,
BK000969,
AK056560,
FO393402,
X81836,
X91906,
AC236430,
AC231645,
AK092049,
AK290940
Ensembl:
ENSG00000171365
KO:
hsa:1184
|
| Nucleutide sequences |
EMBL-CDS:
DAA01544.1,
CAA63000.1,
AAI30430.1,
BAG51748.1,
AAI30432.1,
CAA57430.1,
BAF83629.1,
BAG52474.1
Ensembl_TRS:
ENST00000642885,
ENST00000376088,
ENST00000307367,
ENST00000376091,
ENST00000376108,
ENST00000482218
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304257,
ENSP00000365276,
ENSP00000496632,
ENSP00000365256,
ENSP00000365259,
ENSP00000476732
RefSeq:
NP_001259031.1,
NP_001269092.1,
NP_000075.1,
NP_001121370.1,
XP_016884747.1,
NP_001121371.1,
XP_016884746.1
|
| Others |
UniRef100:
UniRef100_B3KRR2,
UniRef100_A8K4H5,
UniRef100_P51795,
UniRef100_V9GYG7
UniRef90:
UniRef90_V9GYG7,
UniRef90_P51795,
UniRef90_Q9GKE7,
UniRef90_A0A2R8YGW0
UniRef50:
UniRef50_P51791,
UniRef50_A0A2K6GSY5,
UniRef50_V9GYG7
UniGene:
Hs.166486,
Hs.745501
CCDS:
CCDS14328.1,
CCDS48115.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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