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11811 Apobec2

11811

Apobec2

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2

protein-coding

Mus musculus

基因描述

Type Description
Definition apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2

研究结论

Date Results Publications
2018-11-10 12:20:00 Apobec2 deficiency causes mitochondrial defects that increase muscle mitophagy, leading to myopathy and atrophy. Findings demonstrate that Apobec2 is required for mitochondrial homeostasis to maintain normal skeletal muscle function. 29127187
2016-10-01 11:51:00 gene-specific shRNA enhance DNA vaccine immunogenicity 25953029
2012-06-02 11:09:00 Hepatocellular carcinoma developed in 2 of 20 APOBEC2 transgenic mice at 72 weeks of age. 21469143
2010-05-03 11:59:00 Data show that APOBEC2 is preferentially associated with slow-twitch muscle, with its abundance being considerably greater in soleus compared with gastrocnemius muscle and, within soleus muscle, in slow as opposed to fast muscle fibers. 20022958
2010-01-21 00:00:00 both APOBEC2 (despite being an ancestral member of the family with no obvious redundancy in muscle) and APOBEC3 (despite its proposed role in restricting endogenous retrotransposition) are inessential for mouse development, survival, or fertility 16055735

名称对应

Type IDs
Synonymous Arp1
Gene
UniProtKB-ID: ABEC2_MOUSE
UniprotKB: Q9WV35
UniParc: UPI00000011D4
EMBL: BC027530, AF161699
Ensembl: ENSMUSG00000040694, ENSMUSG00000116086
KO: mmu:11811
Nucleutide sequences
EMBL-CDS: AAH27530.1, AAD45361.1
Ensembl_TRS: ENSMUST00000229603, ENSMUST00000046549
Protein sequencees
Ensembl_PRO: ENSMUSP00000047402, ENSMUSP00000155264
RefSeq: NP_033824.1
Others
UniRef100: UniRef100_Q9WV35
UniRef90: UniRef90_Q9Y235
UniRef50: UniRef50_Q9Y235
UniGene: Mm.281793
CCDS: CCDS28868.1

全选

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研究热度

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