| Type | Description |
|---|---|
| Definition | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:24:00 | At an experimental level mouse APOBEC1 is remarkable among 12 mammalian A1 enzymes in that it represents a source of somatic mutations in mouse genome, potentially fueling oncogenesis. | 31726973 |
| 2018-07-07 11:59:00 | APOBEC1-mediated RNA editing occurs within brain microglia cells and is key to maintaining their resting status. Apobec1-/- mice display age-related signs of CNS neurodegeneration. | 29167375 |
| 2018-01-27 10:59:00 | Here, we show that partial loss of either APOBEC1 complementation factor (A1CF), the RNA-binding cofactor of APOBEC1 in RNA editing, or Argonaute 2 (AGO2), a key factor in the biogenesis of certain noncoding RNAs, modulates risk for TGCTs and testicular abnormalities in both parent-of-origin and conventional genetic manners. | 27582469 |
| 2018-01-06 11:22:00 | substantial rearrangement/duplication of transgene elements is present, and transgene integration was accompanied by the deletion of a 19,500 bp fragment of genomic DNA that contains the promoter, exon 1 and part of intron 1 of the APOBEC1 complementation factor (A1cf) gene, as well as several elements that are predicted to regulate chromosomal architecture | 27165291 |
| 2017-09-09 13:44:00 | The observations demonstrate that A1CF does not act as the APOBEC1 complementation factor in vivo under normal physiological conditions and suggest new roles for A1CF, specifically within the male adult kidney. | 28069890 |
| Type | IDs |
|---|---|
| Synonymous | Cdar1 |
| Gene |
UniProtKB-ID:
ABEC1_MOUSE,
Q3U9G8_MOUSE
UniprotKB:
P51908,
Q3U9G8
UniParc:
UPI0000029449
EMBL:
U21950,
U21948,
AK165209,
U22264,
U22262,
U21947,
BC003792,
AK151799,
U21951,
U21949,
U22263,
AK146427
Ensembl:
ENSMUSG00000040613
KO:
mmu:11810
|
| Nucleutide sequences |
EMBL-CDS:
AAC52213.1,
AAH03792.1,
AAC52211.1,
AAC52214.1,
AAC52212.1,
BAE38079.1,
BAE27161.1,
BAE30699.1
Ensembl_TRS:
ENSMUST00000112587,
ENSMUST00000112585,
ENSMUST00000112586
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108206,
ENSMUSP00000108205,
ENSMUSP00000108204
RefSeq:
XP_006505464.1,
XP_011239461.1,
NP_001127863.1,
NP_112436.1
|
| Others |
UniRef100:
UniRef100_P51908
UniRef90:
UniRef90_P51908
UniRef50:
UniRef50_P41238
UniGene:
Mm.3333
CCDS:
CCDS20498.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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