| Type | Description |
|---|---|
| Definition | amyloid beta (A4) precursor-like protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:36:00 | Mutation in Sodium-Glucose Cotransporter 2 Results in Down-Regulation of Amyloid Beta (A4) Precursor-Like Protein 1 in Young Age, Which May Lead to Poor Memory Retention in Old Age. | 32759773 |
| 2017-07-01 10:06:00 | APLP1 exhibits synaptogenic activity, involving trans-synaptic dimerization. APLP1 knock-out mice show impaired basal transmission and a reduced mEPSC frequency. | 28450540 |
| 2016-02-27 10:16:00 | Results suggest that APLP1 deficiency on its own does not lead to defects in synaptic plasticity, but affects synaptic transmission and network inhibition in the dentate gyrus | 25728909 |
| 2012-12-22 11:16:00 | [review] A role of APP and its two closely related homologues APLP1 and APLP2 has been determined in various aspects of nervous system development and function, in particular, for synapse formation and function. | 21931985 |
| 2012-06-30 10:54:00 | findings demonstrated that NB-2 interacts with APLP and that both NB-2 and APLP1 are localized at presynaptic sites, suggesting that NB-2 associates with APLP1 in a cis manner on the presynaptic membrane | 22285261 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
APLP1_MOUSE,
A0A0R4IZZ1_MOUSE,
Q3TUB1_MOUSE
UniprotKB:
Q03157,
A0A0R4IZZ1,
Q3TUB1
UniParc:
UPI000016CA43,
UPI000002953A,
UPI00005B1CA0
EMBL:
AK160871,
AC149067,
BC021877,
L04538
Ensembl:
ENSMUSG00000006651
KO:
mmu:11803
|
| Nucleutide sequences |
EMBL-CDS:
AAH21877.1,
AAA37247.1,
BAE36060.1
Ensembl_TRS:
ENSMUST00000006828
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006828
RefSeq:
NP_031493.2
|
| Others |
UniRef100:
UniRef100_Q03157,
UniRef100_Q3TUB1,
UniRef100_A0A0R4IZZ1
UniRef90:
UniRef90_Q03157
UniRef50:
UniRef50_P51693-2
UniGene:
Mm.2381
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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