| Type | Description |
|---|---|
| Definition | SPEG complex locus |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:33:00 | Striated Preferentially Expressed (SPEG)-Deficient Skeletal Muscles Display Fewer Satellite Cells with Reduced Proliferation and Delayed Differentiation. | 32919980 |
| 2020-08-12 14:40:00 | Data indicate that insulin resistance impairs this protein kinase B (PKB)-Striated muscle preferentially expressed protein kinase (SPEG)-sarcoplasmic/endoplasmic reticulum calcium-ATPase 2a (SERCA2a) signal axis, which contributes to the development of diabetic cardiomyopathy. | 32367034 |
| 2019-12-21 11:41:00 | The 2 kinase-domains of SPEG may play distinct roles to regulate cardiac function. The second kinase-domain of SPEG is a critical regulator for SERCA2a and controls calcium reuptake into the sarcoplasmic reticulum. | 30566039 |
| 2017-05-06 20:26:00 | Acute loss of SPEG in hearts causes junctophilin-2 de-phosphorylation leading to heart failure. | 27729468 |
| 2010-01-21 00:00:00 | Disruption of the striated preferentially expressed gene (Speg) locus leads to cardiac dysfunction and a phenotype consistent with dilated cardiomyopathy. | 19118250 |
| Type | IDs |
|---|---|
| Synonymous | AW125581, Apeg1, BPEG, D1Bwg1450e, SPEGalpha, SPEGbeta, mKIAA1297 |
| Gene |
UniProtKB-ID:
SPEG_MOUSE,
A0A0R4J1J0_MOUSE,
E9QQ25_MOUSE
UniprotKB:
Q62407,
A0A0R4J1J0,
E9QQ25
UniParc:
UPI00005B206F,
UPI0000D720E6,
UPI0000D720E5,
UPI0000029002,
UPI0000D720E7,
UPI0000D8AC04
EMBL:
AK035543,
BC062643,
AC161346,
BC048698,
AK122488,
AK164360,
AF215896,
AC114651,
U57098
Ensembl:
ENSMUSG00000026207
KO:
mmu:11790
|
| Nucleutide sequences |
EMBL-CDS:
AAG34791.1,
BAE37758.1,
AAH62643.1,
BAC65770.1,
AAH48698.3,
AAC52666.1,
BAC29098.1
Ensembl_TRS:
ENSMUST00000113590,
ENSMUST00000122266,
ENSMUST00000113587,
ENSMUST00000113588,
ENSMUST00000113589,
ENSMUST00000087122
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109220,
ENSMUSP00000113646,
ENSMUSP00000109217,
ENSMUSP00000109218,
ENSMUSP00000109219,
ENSMUSP00000084361
RefSeq:
XP_011236948.1,
XP_011236945.1,
XP_030099381.1,
NP_031489.4,
XP_030099372.1,
XP_036011068.1,
XP_011236949.1,
XP_017177843.1,
XP_011236947.1,
XP_006496464.1,
XP_011236946.1,
XP_030099307.1,
XP_030099208.1,
XP_030099250.1,
XP_006496467.1,
XP_030099228.1,
NP_001078839.1,
XP_017177864.1,
XP_030099262.1,
NP_001166948.1,
XP_030099354.1,
XP_017167765.1,
XP_011236953.1,
XP_036011090.1,
XP_011236950.1,
XP_036010913.1,
XP_011236951.1,
XP_006496466.1,
NP_001078840.1,
XP_006496465.1,
XP_030099336.1,
XP_030099133.1,
XP_036011038.1
|
| Others |
UniRef100:
UniRef100_E9QQ25,
UniRef100_A0A0R4J1J0,
UniRef100_Q62407
UniRef90:
UniRef90_Q62407,
UniRef90_A0A0R4J1J0
UniRef50:
UniRef50_S9WLR0,
UniRef50_Q15772
UniGene:
Mm.275397
CCDS:
CCDS48292.1,
CCDS35626.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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