| Type | Description |
|---|---|
| Definition | chloride channel accessory 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:26:00 | Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement. | 31995732 |
| 2020-06-13 11:29:00 | SDR16C5 and SDR16C6 enzymes are not critical for survival but are responsible for most of the retinol dehydrogenase activity in skin, essential for the regulation of the hair-follicle cycle, and required for the maintenance of both sebaceous and meibomian glands | 31570526 |
| 2018-11-10 11:19:00 | Results suggest that CLCA1 is involved in intestinal mucus homeostasis by facilitating processing and removal of mucus to prevent stagnation. | 29885864 |
| 2018-06-23 10:50:00 | CLCA1 suppresses colorectal cancer aggressiveness via inhibition of the Wnt/beta-catenin signaling pathway | 28974231 |
| 2017-06-10 11:08:00 | Increase in TMEM16A activity occurred within minutes of exposure to CLCA1 or after a short treatment with nocodazole, consistent with the hypothesis that CLCA1 stabilizes TMEM16A at the cell surface by preventing its internalization. | 28420732 |
| Type | IDs |
|---|---|
| Synonymous | CACC, CACC1, CLCRG1, CaCC-1, GOB5, hCLCA1, hCaCC-1 |
| Gene |
UniProtKB-ID:
CLCA1_HUMAN
UniprotKB:
A8K7I4
UniParc:
UPI00001AE689
EMBL:
AK314375,
AF039401,
AF039400,
AK291999,
CH471097,
AL122002,
AF127036
Ensembl:
ENSG00000016490
KO:
hsa:1179
|
| Nucleutide sequences |
EMBL-CDS:
AAC95428.1,
AAD25487.1,
EAW73186.1,
BAF84688.1,
AAC95429.1,
BAG37002.1
Ensembl_TRS:
ENST00000234701,
ENST00000394711
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000234701,
ENSP00000378200
RefSeq:
NP_001276.3
|
| Others |
UniRef100:
UniRef100_A8K7I4
UniRef90:
UniRef90_A8K7I4
UniRef50:
UniRef50_A8K7I4
UniGene:
Hs.194659
CCDS:
CCDS709.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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