| Type | Description |
|---|---|
| Definition | apoptotic peptidase activating factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 11:43:00 | CARD9 protects cardiomyocytes from apoptosis by interacting with Apaf-1 and interfering with apoptosome formation following myocardial ischemia/reperfusion injury in vivo and in vitro | 31212066 |
| 2018-07-28 10:42:00 | data collectively demonstrated that Apaf1 is a negative regulator of T cell responses and implicated Apaf1 as a potential target for immunosuppressive drug discovery | 29596528 |
| 2017-08-12 11:14:00 | miR-183 was induced in protective postconditioning and reduced reperfusion injury of the livers via the targeting of apoptotic signaling. miR-183 mediated the tolerance induced by iPoC in livers via Apaf-1 repressing. | 27580417 |
| 2016-07-02 11:15:00 | Apaf1's pivotal role during embryonic development as has been demonstrated to be in regulation of neuronal cell death | 26374523 |
| 2016-06-28 10:45:00 | Inhibition of Caspase-9 restricted, while Apaf-1 promoted, Chlamydia pneumoniae infection in HEp-2, HeLa, and mouse epithelial fibroblast (MEF) cells. | 26290316 |
| Type | IDs |
|---|---|
| Synonymous | 6230400I06Rik, Apaf-1, Apaf1l, fog, mKIAA0413 |
| Gene |
UniProtKB-ID:
APAF_MOUSE,
G3XA09_MOUSE,
Q5DU30_MOUSE
UniprotKB:
O88879,
G3XA09,
Q5DU30
UniParc:
UPI00004E16C6,
UPI00005652F4,
UPI00001E53A9,
UPI000217CB0D
EMBL:
AF064071,
AC138719,
BC131684,
BC131683,
AC140410,
AK220340
Ensembl:
ENSMUSG00000019979
KO:
mmu:11783
|
| Nucleutide sequences |
EMBL-CDS:
AAI31684.1,
AAI31685.1,
AAC62458.1,
BAD90406.1
Ensembl_TRS:
ENSMUST00000159110,
ENSMUST00000020157,
ENSMUST00000162618
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125291,
ENSMUSP00000020157,
ENSMUSP00000124134
RefSeq:
XP_036011453.1,
XP_036011454.1,
NP_033814.2,
XP_036011455.1,
NP_001036023.1,
NP_001269876.1
|
| Others |
UniRef100:
UniRef100_O88879,
UniRef100_G3XA09,
UniRef100_Q5DU30
UniRef90:
UniRef90_O88879
UniRef50:
UniRef50_O14727
UniGene:
Mm.220289
CCDS:
CCDS36030.1,
CCDS70095.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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