| Type | Description |
|---|---|
| Definition | relaxin 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 10:39:00 | Serum level of relaxin-3 hormone is an important mediator in the pathophysiological process of normal puberty being significantly decreased in males with delayed puberty. | 28786126 |
| 2018-01-27 11:32:00 | Therefore, we conclude that stapling of the relaxin3 B chain does not compromise its ability to activate RXFP3 and is a promising method for developing stable peptide agonists and antagonists of RXFP3 to aid relaxin-3/RXFP3 research. | 27498038 |
| 2017-12-16 12:24:00 | the relaxin-3 B-chain C-terminus changes from the original folding-back conformation to an extended conformation during binding with RXFP3, to allow its B27Trp and B26Arg residues to interact with the Trp138 and Glu141 residues of RXFP3, respectively. | 27193232 |
| 2017-11-11 12:49:00 | In a population of acute HF patients, admission relaxin serum levels were associated with clinical and echocardiographic markers of pulmonary hypertension, RV dysfunction, and overload, suggesting a role for circulating relaxin as a biomarker in this setting. | 27488261 |
| 2017-05-13 20:18:00 | the negatively charged transmembrane aspartate residue controls activation of the relaxin-3 receptor RXFP3 | 27353281 |
| Type | IDs |
|---|---|
| Synonymous | H3, RXN3, ZINS4, insl7 |
| Gene |
UniProtKB-ID:
REL3_HUMAN,
K7ENX1_HUMAN,
B2RU28_HUMAN
UniprotKB:
Q8WXF3,
K7ENX1,
B2RU28
UniParc:
UPI0002840B17,
UPI0000042374,
UPI0001747A25
EMBL:
AY358181,
AC022098,
AB076563,
BC140935,
AF447451
Ensembl:
ENSG00000288474,
ENSG00000171136
KO:
hsa:117579
|
| Nucleutide sequences |
EMBL-CDS:
BAC53758.1,
AAL40345.1,
AAQ88548.1,
AAI40936.1
Gene_ORFName:
UNQ6188/PRO20213
Ensembl_TRS:
ENST00000431365,
ENST00000673090,
ENST00000585987
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000500641,
ENSP00000397415,
ENSP00000467130
RefSeq:
NP_001298126.1,
NP_543140.1
|
| Others |
UniRef100:
UniRef100_Q8WXF3,
UniRef100_B2RU28,
UniRef100_K7ENX1
UniRef90:
UniRef90_Q8WXF3,
UniRef90_K7ENX1
UniRef50:
UniRef50_K7ENX1,
UniRef50_Q8WXF3
UniGene:
Hs.352155
CCDS:
CCDS12302.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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