Type | Description |
---|---|
Definition | solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4 |
Date | Results | Publications |
---|---|---|
2020-04-11 11:48:00 | Mice that lack ANT1 show blunted mitophagy and consequent profound accumulation of aberrant mitochondria | 31618756 |
2019-09-14 12:43:00 | By mediating two distinct transport modes, ADP/ATP exchange and H(+) leak, ADP/ATP carrier connects coupled (ATP production) and uncoupled (thermogenesis) energy conversion in mitochondria. | 31341297 |
2019-06-15 12:08:00 | Results suggest that adenine nucleotide translocator 1 (ANT1) modulates interleukin-6 (IL-6) expression through JNK signal pathway in macrophages. | 30311946 |
2018-04-21 10:54:00 | The ANT1-deficient muscle mitochondria produce excess reactive oxygen species and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 and GDF15. | 28223503 |
2017-09-23 12:45:00 | ANT1 can induce autoimmune myocarditis in A/J mice by generating autoreactive T cells. | 27876151 |
Type | IDs |
---|---|
Synonymous | AU019225, Ant1, mANC1 |
Gene |
UniProtKB-ID:
ADT1_MOUSE
UniprotKB:
P48962
UniParc:
UPI0000023829
EMBL:
AF240002,
X74510,
BC026925,
U27315,
BC003791
Ensembl:
ENSMUSG00000031633
KO:
mmu:11739
|
Nucleutide sequences |
EMBL-CDS:
CAA52616.1,
AAH26925.1,
AAC52837.1,
AAF64470.1,
AAH03791.1
Ensembl_TRS:
ENSMUST00000034049
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034049
RefSeq:
NP_031476.3
|
Others |
UniRef100:
UniRef100_P48962
UniRef90:
UniRef90_Q05962
UniRef50:
UniRef50_Q26365
UniGene:
Mm.16228
CCDS:
CCDS40333.1
|
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