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11739 Slc25a4

11739

Slc25a4

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4

研究结论

Date Results Publications
2020-04-11 11:48:00 Mice that lack ANT1 show blunted mitophagy and consequent profound accumulation of aberrant mitochondria 31618756
2019-09-14 12:43:00 By mediating two distinct transport modes, ADP/ATP exchange and H(+) leak, ADP/ATP carrier connects coupled (ATP production) and uncoupled (thermogenesis) energy conversion in mitochondria. 31341297
2019-06-15 12:08:00 Results suggest that adenine nucleotide translocator 1 (ANT1) modulates interleukin-6 (IL-6) expression through JNK signal pathway in macrophages. 30311946
2018-04-21 10:54:00 The ANT1-deficient muscle mitochondria produce excess reactive oxygen species and are partially uncoupled. Hence, the muscle respiration under nonphosphorylating conditions is increased. Muscle transcriptome analysis revealed the induction of mitochondrial biogenesis, down-regulation of diabetes-related genes, and increased expression of the genes encoding the myokines FGF21 and GDF15. 28223503
2017-09-23 12:45:00 ANT1 can induce autoimmune myocarditis in A/J mice by generating autoreactive T cells. 27876151

名称对应

Type IDs
Synonymous AU019225, Ant1, mANC1
Gene
UniProtKB-ID: ADT1_MOUSE
UniprotKB: P48962
UniParc: UPI0000023829
EMBL: AF240002, X74510, BC026925, U27315, BC003791
Ensembl: ENSMUSG00000031633
KO: mmu:11739
Nucleutide sequences
EMBL-CDS: CAA52616.1, AAH26925.1, AAC52837.1, AAF64470.1, AAH03791.1
Ensembl_TRS: ENSMUST00000034049
Protein sequencees
Ensembl_PRO: ENSMUSP00000034049
RefSeq: NP_031476.3
Others
UniRef100: UniRef100_P48962
UniRef90: UniRef90_Q05962
UniRef50: UniRef50_Q26365
UniGene: Mm.16228
CCDS: CCDS40333.1

全选

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研究热度

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