| Type | Description |
|---|---|
| Definition | CASP8 and FADD-like apoptosis regulator |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 10:54:00 | c-FLIP expression was significantly decreased in organs of septic rats compared with control rats, and that c-FLIP overexpression protected HUVECs from LPS+CHX-induced apoptosis in vitro. | 28498469 |
| 2017-02-25 10:50:00 | Estradiol increased c-FLIPlong expression in anterior pituitary cells but not in GH3 cells. | 26566102 |
| 2015-06-20 11:22:00 | Our results also suggest that emodin regulates cFLIP expression in transcriptional level. | 24691542 |
| 2012-01-14 11:12:00 | data suggest that caspase-8 does not become activated through an extrinsic but an "intrinsic/intracellular" apoptotic pathway unleashed by the down-regulation of c-FLIP by c-Myc | 21903094 |
| 2010-05-31 11:24:00 | we uncover a new role for FLIP-L as an unexpected critical player in neurotrophin-induced mitogen-activated protein kinase/ERK- and NF-B-mediated control of neurite growth in developing neurons | 20427667 |
| Type | IDs |
|---|---|
| Synonymous | Flip |
| Gene |
UniProtKB-ID:
Q99MZ5_RAT,
C0H5Y5_RAT
UniprotKB:
Q99MZ5,
C0H5Y5
UniParc:
UPI00004C9664,
UPI00000E8467
EMBL:
CH473965,
AC123462,
AF244366,
BC089781
Ensembl:
ENSRNOG00000012473
KO:
rno:117279
|
| Nucleutide sequences |
EMBL-CDS:
EDL98982.1,
AAK28358.1,
EDL98981.1,
EDL98980.1,
AAH89781.1
Gene_ORFName:
rCG_22405,
rCG_22405
Ensembl_TRS:
ENSRNOT00000016730
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016730
RefSeq:
XP_006245011.1,
NP_001029036.1,
XP_017451738.1,
XP_006245009.1,
NP_476479.1,
XP_006245008.1,
XP_006245010.1,
XP_006245012.1
|
| Others |
UniRef100:
UniRef100_C0H5Y5,
UniRef100_Q99MZ5
UniRef90:
UniRef90_Q99MZ5,
UniRef90_C0H5Y5
UniRef50:
UniRef50_O15519-2,
UniRef50_O35732
UniGene:
Rn.204752
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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