| Type | Description |
|---|---|
| Definition | MAS related GPR family member X2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:28:00 | Immunoglobulin E cross-linking or MRGPRX2 activation: clinical insights from rocuronium hypersensitivity. | 33153719 |
| 2020-11-21 13:31:00 | Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Functions. | 32038646 |
| 2020-04-25 10:36:00 | Gold chloride induces a pseudo-allergic reaction via MRGPRX2 both in vitro and in vivo. | 31076078 |
| 2020-03-07 10:30:00 | Conserved residues in TM6 (I225) and TM7 (Y279) of MRGPRX2 are essential for SP-induced Ca2+ mobilization and mast cell activation by substance P. | 31652731 |
| 2019-12-14 10:50:00 | Study investigated whether thimerosal induces pseudo-allergic reactions directly through MrgprB2 and MRGPRX2 on mast cells in vitro and in vivo and revealed that MrgprB2 mediates thimerosal-induced mast cell degranulation and pseudo-allergic reaction in mice. MRGPRX2 may be a key contributor to human contact dermatitis. | 31558225 |
| Type | IDs |
|---|---|
| Synonymous | MGRG3, MRGX2 |
| Gene |
UniProtKB-ID:
MRGX2_HUMAN
UniprotKB:
Q96LB1
UniParc:
UPI0000038C81
EMBL:
AY651152,
AY651145,
AY651133,
AY651132,
AY651139,
CH471064,
EU883579,
AY651135,
HG426071,
AB065811,
AY651140,
BC063450,
AY651130,
AY651157,
AY651138,
AY651141,
AY651151,
AY651134,
AY651147,
AY651155,
AY651131,
AY651144,
AY845176,
AY651150,
AY651158,
AY651146,
AY651137,
AY651161,
AY651149,
AY651156,
AY651142,
AY042214,
AY651159,
AY651160,
AY651153,
AY651136,
AY651154,
AY651148,
AY845175,
AB083626,
AY651143
Ensembl:
ENSG00000183695
KO:
hsa:117194
|
| Nucleutide sequences |
EMBL-CDS:
AAW70058.1,
AAW70069.1,
AAW70044.1,
AAK91805.1,
AAW70073.1,
AAW70063.1,
CDG86189.1,
AAW70046.1,
AAW70059.1,
AAW70053.1,
AAW70064.1,
BAB89339.1,
AAW70061.1,
AAW70066.1,
AAW70052.1,
AAW70072.1,
AAW70048.1,
AAW70057.1,
AAH63450.1,
BAC06030.1,
AAW70067.1,
AAW70065.1,
AAW70071.1,
AAW70054.1,
AAW70074.1,
AAW70050.1,
AAW70070.1,
AAW70062.1,
AAW70056.1,
AAW70051.1,
AAW70068.1,
AAW70047.1,
AAW70082.1,
EAW68359.1,
ACG60653.1,
AAW70083.1,
AAW70060.1,
AAW70043.1,
AAW70049.1,
AAW70055.1,
AAW70045.1
Ensembl_TRS:
ENST00000329773
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333800
RefSeq:
NP_001290544.1,
NP_473371.1
|
| Others |
UniRef100:
UniRef100_Q96LB1
UniRef90:
UniRef90_Q96LB1
UniRef50:
UniRef50_Q96LB1
UniGene:
Hs.350566
CCDS:
CCDS7847.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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