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117177 RAB3IP

117177

RAB3IP

RAB3A interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAB3A interacting protein

研究结论

Date Results Publications
2021-03-06 13:26:00 Rab8 and Rabin8-Mediated Tumor Formation by Hyperactivated EGFR Signaling via FGFR Signaling. 33092268
2020-06-27 10:43:00 C7orf43 directly binds to Rabin8 and that C7orf43 knockdown diminishes Rabin8 preciliary centrosome accumulation. 31467083
2019-02-09 13:09:00 The crystal structure of tetrameric Rabin8, guanine nucleotide exchange factors (GEFs) domain reveals an occluded Rab8 binding site suggesting that this oligomer is enzymatically inactive, a notion that's verified experimentally using Rabin8/Rab8 GEF assays. 29318657
2019-01-19 11:33:00 role of Rab3IP in inducing an invasive phenotype in gastric cancer cells, in addition to its involvement in EMT. 30005870
2016-05-07 11:08:00 Authors show that Rab11-GMPPNP-FIP3-Rabin8 is more stable than Rab11-GMPPNP-Rabin8, owing to direct interaction between Rabin8 and FIP3 within the dual effector-bound complex. 26258637

名称对应

Type IDs
Synonymous RABIN3, RABIN8
Gene
UniProtKB-ID: RAB3I_HUMAN
UniprotKB: Q96QF0
UniParc: UPI000006D012, UPI00000372CF, UPI000006E4D2, UPI0000071C93, UPI0000551C97, UPI000006EB02, UPI0000072C88, UPI000006FDD0
EMBL: AJ312899, BC059358, AK027671, AJ312901, BC015548, AJ312900, AK026201, AJ312898, AK027566, AC025263, AJ312896, AJ312897
Ensembl: ENSG00000127328
KO: hsa:117177
Nucleutide sequences
EMBL-CDS: BAB15391.1, CAC59836.1, BAB55202.1, CAC59839.1, AAH15548.1, CAC59837.1, BAB55283.1, AAH59358.1, CAC59840.1, CAC59838.1, CAC59835.1
Ensembl_TRS: ENST00000417413, ENST00000247833, ENST00000483530, ENST00000362025, ENST00000378815, ENST00000552199, ENST00000550536, ENST00000553099, ENST00000551641
Protein sequencees
Ensembl_PRO: ENSP00000448944, ENSP00000436304, ENSP00000368092, ENSP00000447300, ENSP00000448773, ENSP00000419216, ENSP00000247833, ENSP00000355381, ENSP00000448027
RefSeq: XP_016874263.1, XP_006719290.3, NP_783322.1, XP_006719289.3, NP_071901.2, NP_001265331.1, NP_001019818.1, XP_024304600.1, XP_016874262.1, XP_016874264.1, NP_783323.1, XP_016874266.1, NP_783324.1
Others
UniRef100: UniRef100_Q96QF0
UniRef90: UniRef90_Q96QF0
UniRef50: UniRef50_Q96QF0
UniGene: Hs.258209
CCDS: CCDS44942.1, CCDS8993.1, CCDS8995.1, CCDS8996.1, CCDS41811.1

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研究热度

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