| Type | Description |
|---|---|
| Definition | adenosine monophosphate deaminase 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-14 12:38:00 | Data show that AMP deaminase 3 (Ampd3)-/-/5'-nucleotidase (CD73)-/- knockout mice are more sensitive to AMP-induced hypometabolism than mice with a single enzyme deficiency, which are more sensitive than wild type. | 28746349 |
| 2017-08-19 10:42:00 | depletion of the epigenome modifier histone deacetylase 3 (HDAC3) specifically in skeletal muscle causes severe systemic insulin resistance in mice but markedly enhances endurance and resistance to muscle fatigue, despite reducing muscle force. This is due to lower glucose utilization and greater lipid oxidation in HDAC3-depleted muscles, a fuel switch caused by the activation of anaplerotic reactions driven by Ampd3. | 27991918 |
| 2017-08-05 10:43:00 | Mice carrying the mutation exhibit rapid RBC turnover, with increased erythropoiesis, dramatically shortened RBC lifespan, and signs of increased RBC senescence/eryptosis, suggesting a key role for AMPD3 in determining RBC half-life. Mice were also found to be resistant to infection with the rodent malaria Plasmodium chabaudi. | 27465915 |
| 2016-07-30 11:05:00 | Erythrocytes from Ampd3(-/-) mice exhibited higher half-saturation pressure of oxygen. | 26249166 |
| 2015-02-21 10:47:00 | effect of AMP-deaminase 3 knock-out in mice on enzyme activity in heart and other organs | 24940686 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
AMPD3_MOUSE,
A0A1L1SRX2_MOUSE
UniprotKB:
O08739,
A0A1L1SRX2
UniParc:
UPI0003D727D9,
UPI0000020EE7
EMBL:
BC040366,
AK133465,
D88994,
D85596,
AC122844,
BC056380,
CH466531
Ensembl:
ENSMUSG00000005686
KO:
mmu:11717
|
| Nucleutide sequences |
EMBL-CDS:
AAH56380.1,
BAA19933.1,
BAA32548.1,
EDL16989.1,
EDL16988.1,
AAH40366.1,
BAE21671.1,
EDL16990.1
Ensembl_TRS:
ENSMUST00000170374,
ENSMUST00000005829,
ENSMUST00000213373
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000130495,
ENSMUSP00000005829,
ENSMUSP00000149655
RefSeq:
NP_001359370.1,
XP_006507280.2,
NP_001359368.1,
XP_036008473.1,
XP_030097862.1,
XP_036008472.1,
NP_033797.2,
XP_006507282.2,
NP_001263230.1,
XP_006507285.1
|
| Others |
UniRef100:
UniRef100_O08739,
UniRef100_A0A1L1SRX2
UniRef90:
UniRef90_O09178,
UniRef90_Q01432
UniRef50:
UniRef50_Q01432
UniGene:
Mm.3238
CCDS:
CCDS21747.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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