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117148 Necab2

117148

Necab2

N-terminal EF-hand calcium binding protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition N-terminal EF-hand calcium binding protein 2

研究结论

Date Results Publications
2020-05-30 11:42:00 We identified over 100 proteins with robustly enriched expression in area CA2 compared to CA1. Many of these proteins, including RGS14 and NECAB2, have already been shown to be enriched in CA2 and important for its function, while many more merit further study in the context of enhanced expression in this enigmatic brain region. 31059263
2019-09-28 13:25:00 NECAB2 was downregulated by peripheral nerve injury, leading to the hypothesis that NECAB2 loss of function could limit pain sensation. Indeed, Necab2-/- mice reached a pain-free state significantly faster after peripheral inflammation than did WT littermates. 29893745
2014-03-22 11:40:00 The genes for the three Necab's, including Necab-2, were expressed in specific, non-overlapping areas of the hippocampus. 23850650

名称对应

Type IDs
Synonymous Efcbp2
Gene
UniProtKB-ID: NECA2_MOUSE
UniprotKB: Q91ZP9
UniParc: UPI0000029866, UPI0000D6417B
EMBL: BC115963, AF411253, BC115857, AK082727
Ensembl: ENSMUSG00000031837
KO: mmu:117148
Nucleutide sequences
EMBL-CDS: AAI15964.1, AAL04151.1, AAI15858.1, BAC38589.1
Ensembl_TRS: ENSMUST00000098363
Protein sequencees
Ensembl_PRO: ENSMUSP00000095966
RefSeq: XP_036009620.1, XP_036009621.1, NP_473436.1, XP_017168015.1
Others
UniRef100: UniRef100_Q91ZP9
UniRef90: UniRef90_F1LQY6
UniRef50: UniRef50_F1LQY6
UniGene: Mm.356184
CCDS: CCDS22705.1

全选

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研究热度

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