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117145 THEM4

117145

THEM4

thioesterase superfamily member 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition thioesterase superfamily member 4

研究结论

Date Results Publications
2018-05-12 10:30:00 Results find that head and neck squamous cell carcinoma (HNSCC) tumor tissues and cell lines had high levels of CTMP expression. These data suggest that CTMP functions as a positive regulator of Akt and facilitates HNSCC invasion such as LN metastasis by regulating EMT in a Snail-dependent manner indicating the oncogenic activity of CTMP in HNSCC, and its expression is an independent predictor of clinical prognosis. 27328758
2018-03-10 11:37:00 CTMP expression may be considered as a prognostic biomarker in HER2-enriched breast cancer and high expression may indicate a utility for AKT-inhibition in these patients. 27447863
2012-06-30 10:26:00 Suggest that CTMP may therefore play a critical role in mitochondrial-mediated apoptosis in lung cancer cells. 22200884
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20877624
2010-03-01 11:04:00 Data show low or moderate methylation was found in seven selected genes BAD, BBC3, CAV1, CDK2AP1, NPM1, PRKCDBP and THEM4. 19679565

名称对应

Type IDs
Synonymous CTMP
Gene
UniProtKB-ID: THEM4_HUMAN, A8K0C9_HUMAN
UniprotKB: Q5T1C6, A8K0C9
UniParc: UPI000045625A, UPI000006DC16
EMBL: AL450992, CH471121, AK289494, AJ313515, BC065277, AK314852
Ensembl: ENSG00000159445
KO: hsa:117145
Nucleutide sequences
EMBL-CDS: CAC86384.1, EAW53400.1, BAG37369.1, AAH65277.1, BAF82183.1
Ensembl_TRS: ENST00000368814
Protein sequencees
Ensembl_PRO: ENSP00000357804
RefSeq: NP_444283.2, XP_011507444.1
Others
UniRef100: UniRef100_A8K0C9, UniRef100_Q5T1C6
UniRef90: UniRef90_Q5T1C6, UniRef90_F6XC58
UniRef50: UniRef50_E9PLJ7, UniRef50_Q5T1C6
UniGene: Hs.164070
CCDS: CCDS1006.1

全选

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