| Type | Description |
|---|---|
| Definition | cation channel sperm associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-21 10:53:00 | Catsper1 tyrosine phosphorylation functions as an intracellular sensor for Ca (2+) entry in human sperm through regulation of cytoplasmic pH. | 30203545 |
| 2019-08-10 12:21:00 | The human CATSPER1 promoter is positively regulated in vitro by CREB-A in HEK293 and GC1-spg cells. Both lines showed differential transcriptional regulation, which was defined by the factors and coactivators present in each cell line as well as the context in which the CRE sites were found in the promoter. | 30017233 |
| 2019-03-30 11:41:00 | results show that the transcriptional factor SRY specifically binds to different sites in the promoter sequence and has the ability to control CATSPER1 gene transcription. | 30379860 |
| 2018-05-12 10:57:00 | explored whether steroid hormones to which human spermatozoa are exposed in the male and female genital tract influence CatSper activation via modulation of ABHD2 | 28507119 |
| 2017-09-30 14:16:00 | Electrophysiological studies showed a significant increase in Cd(2+) and manganese (Mn(2+)) currents through the CaV3.1 mutants as well as a reduction in the inhibitory effect of Cd(2+) on the Ca(2+) current. | 27134080 |
| Type | IDs |
|---|---|
| Synonymous | CATSPER, SPGF7 |
| Gene |
UniProtKB-ID:
CTSR1_HUMAN
UniprotKB:
Q8NEC5
UniParc:
UPI000045651C
EMBL:
AP006287,
BC036522,
BC032950,
AF407333
Ensembl:
ENSG00000175294
KO:
hsa:117144
|
| Nucleutide sequences |
EMBL-CDS:
AAH32950.1,
AAL14105.1,
AAH36522.1
Ensembl_TRS:
ENST00000312106
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309052
RefSeq:
NP_444282.3
|
| Others |
UniRef100:
UniRef100_Q8NEC5
UniRef90:
UniRef90_Q8NEC5
UniRef50:
UniRef50_Q8NEC5
UniGene:
Hs.189105
CCDS:
CCDS8127.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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