| Type | Description |
|---|---|
| Definition | ubiquitin protein ligase E3 component n-recognin 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:07:00 | UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. | 31093990 |
| 2015-12-05 10:26:00 | results confirm the role of the MLLE domain of UBR5 in substrate recruitment and suggest a potential role in regulating UBR5 ligase activity. | 26224628 |
| 2010-01-21 00:00:00 | PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein | 16554297 |
| Type | IDs |
|---|---|
| Synonymous | Dd5, Rat100 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_017450714.1,
XP_006241632.2,
XP_008763704.1,
XP_008763690.1,
XP_006226121.1,
XP_008774684.1,
XP_008763691.1
|
| Others |
UniGene:
Rn.54812
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31093990 |
J. Physiol. (Lond.) Robert A Seaborne , David C Hughes , Daniel C Turner , Daniel J Owens , Leslie M Baehr , Piotr Gorski , Ekaterina A Semenova , Oleg V Borisov , Andrey K Larin , Daniil V Popov , Edward V Generozov , Hazel Sutherland , Ildus I Ahmetov , Jonathan C Jarvis , Sue C Bodine , Adam P Sharples |
2019-07-01 | - |
| 28689657 |
Mol Cell Joshua E Flack , Juliusz Mieszczanek , Nikola Novcic , Mariann Bienz |
2017-07-20 | - |
| 26514267 |
J. Pineal Res. Abla Benleulmi-Chaachoua , Lina Chen , Kate Sokolina , Victoria Wong , Igor Jurisica , Michel Boris Emerit , Michèle Darmon , Almudena Espin , Igor Stagljar , Petra Tafelmeyer , Gerald W Zamponi , Philippe Delagrange , Pascal Maurice , Ralf Jockers |
2016-01-01 |
MTNR1B,
TRIP12
|
| 26224628 |
J Biol Chem Juliana Muñoz-Escobar , Edna Matta-Camacho , Guennadi Kozlov , Kalle Gehring |
2015-09-11 | - |
| 25470037 |
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells. Nature Sascha Rutz , Nobuhiko Kayagaki , Qui T Phung , Celine Eidenschenk , Rajkumar Noubade , Xiaoting Wang , Justin Lesch , Rongze Lu , Kim Newton , Oscar W Huang , Andrea G Cochran , Mark Vasser , Benjamin P Fauber , Jason DeVoss , Joshua Webster , Lauri Diehl , Zora Modrusan , Donald S Kirkpatrick , Jennie R Lill , Wenjun Ouyang , Vishva M Dixit |
2015-02-19 |
Parp1,
Il17a,
Rag2,
Rorc,
Otud5,
Ubr5
|
| 24002223 |
Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat. Rev. Mol. Cell Biol. Stephanie Panier , Daniel Durocher |
2013-10-01 |
Vcp,
Ubr5,
Ppp6c,
Ppp4c,
Ppp2ca,
Ppm1d,
Usp16,
Rnf4,
Otub1,
Pias1,
Mdc1,
Psmd14,
L3mbtl1,
Eya3,
Kdm4a,
Usp44,
Trip12,
Brcc3,
Pias4,
Usp3,
Baz1b,
H2afx,
Eya1
|
| 22884692 |
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell Thorkell Gudjonsson , Matthias Altmeyer , Velibor Savic , Luis Toledo , Christoffel Dinant , Merete Grøfte , Jirina Bartkova , Maria Poulsen , Yasuyoshi Oka , Simon Bekker-Jensen , Niels Mailand , Beate Neumann , Jean-Karim Heriche , Robert Shearer , Darren Saunders , Jiri Bartek , Jiri Lukas , Claudia Lukas |
2012-08-17 |
RNF168,
UBR5,
TRIP12
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21118991 |
The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin. Mol Biol Cell Avital Hay-Koren , Michal Caspi , Alona Zilberberg , Rina Rosin-Arbesfeld |
2011-02-01 | - |
| 19946888 |
Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins |
2010-01-01 |
MED6,
PDCD6IP,
MED16,
PIGK,
DNAJB6,
FARSB,
DNM1L,
ABCF2,
HUWE1,
ARPC3,
ACTR3,
ACTR2,
RAD50,
PREB,
ACTR1B,
LRPPRC,
TRAP1,
BCAP31,
PLXNC1,
LPCAT3,
TNK2,
PSME3,
MPHOSPH9,
FLOT1,
DDX39A,
AK6,
ADAM10,
PLIN3,
CALCOCO2,
CDK9,
ABCC4,
ZMPSTE24,
AKAP8,
BET1,
MARCH6,
KATNB1,
ADAR,
EMC8,
BTN3A3,
ATP8A1,
NDC80,
CDIPT,
PGRMC2,
TUBGCP3,
ECI2,
COG5,
SLC25A17,
LRRC41,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
HYOU1,
IPO7,
NOP56,
ARL6IP5,
HTATIP2,
AGPAT1,
ARFGEF2,
RABAC1,
SLU7,
PRPF8,
PAICS,
CENPE,
PMVK,
KHDRBS1,
CELF1,
GNA13,
CFL1,
MGEA5,
YME1L1,
STAG2,
CTSC,
GIPC1,
HBS1L,
TUBGCP2,
PGRMC1,
MAN1A2,
PNPLA6,
MAGED2,
ADCY3,
EHD1,
TOMM34,
ERP29,
YWHAQ,
ASCC3,
GCN1,
IMMT,
ILVBL,
SLC27A4,
SLC27A3,
KIF2C,
GLIPR1,
CPSF6,
DDX52,
WWP2,
CNTRL,
CHD4,
KRR1
|
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