| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E |
| Date | Results | Publications |
|---|---|---|
| 2016-04-23 11:19:00 | Cerebral ischemia and subsequent reperfusion induced dephosphorylation and phosphorylation of 4E-BP2 at Thr37/Thr46. The induced phosphorylation coincided with the release of 4E-BP2 from eIF4E, although two phosphorylated 4E-BP2 forms were bound to eIF4E. | 25822952 |
| 2016-01-16 10:57:00 | Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, resulting in caspase-dependent and -independent apoptosis in neuronal cells. | 25304210 |
| 2014-03-22 10:11:00 | Expression of eIF4E in hippocampus is higher in vascular dementia treated with electroacupuncture compared to untreated. | 23053837 |
| 2013-11-16 10:04:00 | TGFbeta induces signaling involving PI3kinase-dependent Mnk-1-mediated phosphorylation of eIF4E at Ser-209 to facilitate mesangial cell hypertrophy. A role for dissociation of 4EBP-1-eIF4E complex for Mnk-1-mediated phosphorylation of eIF4E. | 23359369 |
| 2011-12-06 11:36:00 | At birth increased Po(2) acts with glucocorticosteroid through an mTOR-related pathway to increase alpha-ENaC protein synthesis, thereby promoting lung fluid absorption. | 17556672 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IF4E_RAT
UniprotKB:
P63074
UniParc:
UPI00000018EA
EMBL:
X83399,
BC087001
Ensembl:
ENSRNOG00000052343
KO:
rno:117045
|
| Nucleutide sequences |
EMBL-CDS:
CAA58316.1,
AAH87001.1
Ensembl_TRS:
ENSRNOT00000090526
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000073799
RefSeq:
XP_017446081.1,
NP_446426.1,
XP_008759710.1
|
| Others |
UniRef100:
UniRef100_P63073
UniRef90:
UniRef90_P63073
UniRef50:
UniRef50_P63073
UniGene:
Rn.11275
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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