p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes.

Biochim Biophys Acta Mol Cell Res     Audrey-Ann Dumont , Lauralyne Dumont , Jonathan Berthiaume , Mannix Auger-Messier

The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.

Mol. Cell     Lu Deng , Cong Jiang , Lei Chen , Jiali Jin , Jie Wei , Linlin Zhao , Minghui Chen , Weijuan Pan , Yan Xu , Hongshang Chu , Xinbo Wang , Xin Ge , Dali Li , Lujian Liao , Mingyao Liu , Li Li , Ping Wang

Regulation of mTORC1 by amino acids.

Trends Cell Biol.     Liron Bar-Peled , David M Sabatini

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.

Science     Liron Bar-Peled , Lynne Chantranupong , Andrew D Cherniack , Walter W Chen , Kathleen A Ottina , Brian C Grabiner , Eric D Spear , Scott L Carter , Matthew Meyerson , David M Sabatini

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

Cell     Jung Min Han , Seung Jae Jeong , Min Chul Park , Gyuyoup Kim , Nam Hoon Kwon , Hoi Kyoung Kim , Sang Hoon Ha , Sung Ho Ryu , Sunghoon Kim

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.

Cell     Yasemin Sancak , Liron Bar-Peled , Roberto Zoncu , Andrew L Markhard , Shigeyuki Nada , David M Sabatini

Molecular mechanisms of mTOR-mediated translational control.

Nat. Rev. Mol. Cell Biol.     Xiaoju Max Ma , John Blenis

Integral and associated lysosomal membrane proteins.

Traffic     Bernd Schröder , Christian Wrocklage , Cuiping Pan , Ralf Jäger , Bernd Kösters , Helmut Schäfer , Hans-Peter Elsässer , Matthias Mann , Andrej Hasilik

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.     Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team