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116988 AGAP3

116988

AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

研究结论

Date Results Publications
2019-01-12 10:37:00 AGAP3 expression was significantly increased in colorectal cancer (CRC)and colorectal adenoma compared to normal tissue. CRAG overexpression up-regulated c-Jun expression, and significantly increased cell proliferation and colony formation capability. AGAP3 expression did not have a concordant association with patient prognosis among datasets 30591445
2013-10-19 13:32:00 AGAP3 is an essential signaling component of the NMDA receptor complex that links NMDA receptor activation to AMPA receptor trafficking. 23904596
2010-01-21 00:00:00 M-RIP can assemble a complex containing both RhoA and Myosin phosphatase myosin binding subunit, suggesting that M-RIP may play a role in myosin phosphatase regulation by RhoA 14506264

名称对应

Type IDs
Synonymous AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3
Gene
UniProtKB-ID: AGAP3_HUMAN, E7ESL9_HUMAN, D3DX07_HUMAN, Q86ST5_HUMAN, Q86XV5_HUMAN, C9J975_HUMAN
UniprotKB: Q96P47, E7ESL9, D3DX07, Q86ST5, Q86XV5, C9J975
UniParc: UPI00001274CE, UPI0000EE7B59, UPI00001A8241, UPI0000DAC777, UPI0001B792F8, UPI0000246FFA, UPI000000DAA4, UPI00000734F3, UPI000017DF72, UPI0000D720A5, UPI0000DAC778
EMBL: AF413079, AC010973, AB209781, AF359283, AK055393, BC044644, BC048300, CH471173
Ensembl: ENSG00000133612
KO: hsa:116988
Nucleutide sequences
EMBL-CDS: BAG51510.1, EAW54028.1, BAD93018.1, EAW54026.1, AAK48932.2, AAL04173.1, EAW54025.1, EAW54029.1, AAH44644.1, AAH48300.1
Gene_ORFName: hCG_18694
Ensembl_TRS: ENST00000397238, ENST00000622464, ENST00000463381, ENST00000473312, ENST00000335367, ENST00000479901
Protein sequencees
Ensembl_PRO: ENSP00000418016, ENSP00000418921, ENSP00000480655, ENSP00000380413, ENSP00000335589, ENSP00000418125
RefSeq: NP_001337031.1, NP_001337033.1, XP_011514082.1, XP_016867224.1, NP_001295233.1, NP_001036000.1, NP_114152.3, NP_001268229.1, NP_001295234.1, NP_001337032.1
Others
UniRef100: UniRef100_E7ESL9, UniRef100_Q86ST5, UniRef100_Q96P47, UniRef100_D3DX07, UniRef100_Q86XV5, UniRef100_C9J975
UniRef90: UniRef90_Q96P47, UniRef90_A0A096NZN2, UniRef90_A0A0G2JDW1, UniRef90_Q86XV5, UniRef90_Q96P47-6
UniRef50: UniRef50_Q96P47, UniRef50_A0A0G2JDW1, UniRef50_Q96P47-6, UniRef50_G3RL72
UniGene: Hs.647075
CCDS: CCDS55185.1, CCDS43681.1, CCDS64802.1

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