| Type | Description |
|---|---|
| Definition | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:53:00 | AGAP1 regulates subcellular localization of FilGAP and control cancer cell invasion. | 31785816 |
| 2020-04-11 10:35:00 | 2 Arf GAPs, ASAP1 and AGAP1, have been found to bind directly to and influence the activity of myosins and kinesins, motor proteins associated with filamentous actin and microtubules, respectively. | 28430047 |
| 2017-09-23 13:38:00 | The effect of AGAP1 Knockdown could be rescued by FLAG-AGAP1, but not by an AGAP1 mutant that did not bind Kif2A efficiently, ArfGAP1-HA or Kif2A-GFP. The results support the hypothesis that the Kif2A.AGAP1 complex contributes to control of cytoskeleton remodeling involved in cell movement. | 27531749 |
| 2012-07-28 11:05:00 | GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. | 22453919 |
| 2010-01-21 00:00:00 | CENTG2 is an intriguing candidate gene that merits further scrutiny for its role in autism. | 15892143 |
| Type | IDs |
|---|---|
| Synonymous | AGAP-1, CENTG2, GGAP1, cnt-g2 |
| Gene |
UniProtKB-ID:
AGAP1_HUMAN,
B2RZG9_HUMAN,
X5D293_HUMAN
UniprotKB:
Q9UPQ3,
B2RZG9,
X5D293
UniParc:
UPI000000D809,
UPI000176162C,
UPI00001AED9A,
UPI000387BF6B,
UPI00005E1AE1
EMBL:
AF413078,
AC079400,
BC060814,
BC167153,
AC073989,
AC012305,
AC064874,
BC167157,
AB029022,
KJ534764,
AY033765,
BC140856,
AC019047,
AK001722
Ensembl:
ENSG00000157985
KO:
hsa:116987
|
| Nucleutide sequences |
EMBL-CDS:
AAL04172.1,
AAH60814.1,
AAI40857.1,
BAA91862.1,
BAA83051.2,
AAK56506.1,
AAI67153.1,
AAI67157.1,
AHW56404.1
Ensembl_TRS:
ENST00000409457,
ENST00000304032,
ENST00000336665
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000338378,
ENSP00000387174,
ENSP00000307634
RefSeq:
XP_024308440.1,
XP_024308447.1,
NP_001032208.1,
XP_024308444.1,
XP_016858771.1,
NP_001231817.1,
XP_011508851.1,
XP_006712298.1,
XP_005246116.1,
XP_011508850.1,
NP_055729.2,
XP_006712302.2,
XP_024308446.1,
XP_006712300.2,
XP_006712297.1,
XP_011508849.1
|
| Others |
UniRef100:
UniRef100_B2RZG9,
UniRef100_Q9UPQ3,
UniRef100_X5D293
UniRef90:
UniRef90_X5D293,
UniRef90_Q9UPQ3,
UniRef90_B2RZG9
UniRef50:
UniRef50_H2MT15,
UniRef50_A0A2R9B9E0,
UniRef50_Q9UPQ3
UniGene:
Hs.435039
CCDS:
CCDS2514.1,
CCDS33408.1,
CCDS58756.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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