| Type | Description |
|---|---|
| Definition | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:31:00 | Exosomes derived from microRNA-199a-overexpressing mesenchymal stem cells inhibit glioma progression by down-regulating AGAP2. | 31386624 |
| 2020-06-27 12:15:00 | chromatin immunoprecipitation studies revealed the presence of RARalpha, RXRalpha and the lysine acetyl transferase PCAF in AGAP2 promoter. | 30674964 |
| 2019-09-14 11:49:00 | The role of AGAP2 in the pro-fibrogenic phenotype of hepatic stellate cells in response to TGFbeta. | 30660615 |
| 2018-04-28 12:02:00 | A pleckstrin homology domain in PIKE-L directly binds alpha-synuclein and antagonizes its aggregation. Accordingly, PIKE-L overexpression decreases dopaminergic cell death elicited by MPP(+), whereas PIKE-L knockdown elevates alpha-synuclein oligomerization and cell death. | 28096359 |
| 2017-09-30 12:45:00 | these findings support that PIKE amplification or overexpression coordinately acts with CDK4 to drive glioblastoma tumorigenesis. | 28368413 |
| Type | IDs |
|---|---|
| Synonymous | CENTG1, GGAP2, PIKE |
| Gene |
UniProtKB-ID:
AGAP2_HUMAN,
A0A024RB55_HUMAN,
F8VVT9_HUMAN
UniprotKB:
Q99490,
A0A024RB55,
F8VVT9
UniParc:
UPI00001AF80C,
UPI0000074473,
UPI00000012B8
EMBL:
U81031,
AY128689,
AF384128,
D79989,
BC028020,
CH471054,
AC025165,
AK292672,
AF413077
Ensembl:
ENSG00000135439
KO:
hsa:116986
|
| Nucleutide sequences |
EMBL-CDS:
AAM97540.1,
BAA11484.2,
BAF85361.1,
AAH28020.1,
AAL04171.1,
AAC39522.2,
AAO39848.1,
EAW97049.1,
EAW97051.1,
EAW97050.1
Gene_ORFName:
hCG_40148
Ensembl_TRS:
ENST00000257897,
ENST00000547588
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000257897,
ENSP00000449241
RefSeq:
XP_005268683.1,
XP_016874261.1,
NP_055585.1,
XP_005268682.1,
NP_001116244.1
|
| Others |
UniRef100:
UniRef100_A0A024RB55,
UniRef100_F8VVT9,
UniRef100_Q99490
UniRef90:
UniRef90_A0A024RB55,
UniRef90_Q99490
UniRef50:
UniRef50_G1U4T3,
UniRef50_Q99490
UniGene:
Hs.302435
CCDS:
CCDS8951.1,
CCDS44932.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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