| Type | Description |
|---|---|
| Definition | growth factor, augmenter of liver regeneration |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 11:18:00 | In gain-of-function studies using mice overexpressing the human resolvin E1 receptor (ERV1) in myeloid cells, monocyte phenotypic shifts to increased patrolling-to-inflammatory ratio controlled inflammation, reduced body weight gain and protected from hyperglycemia on high-fat diet. | 28993702 |
| 2018-12-22 11:21:00 | Study in mouse model of liver cirrhosis demonstrate that the lack of ALR aggravates liver fibrosis, probably by regulating mitochondrial Ca2+ homeostasis and mitochondrial dynamics in hepatic stellate cells. | 30251695 |
| 2018-10-27 10:12:00 | To test whether differences in the ratio between CHCHD4 and ALR might explain tissue-specific differences in the CHCHD4 redox state, we determined the molar ratio of both proteins in different mouse tissues. Surprisingly, ALR is superstoichiometric over CHCHD4 in most tissues. | 29704824 |
| 2017-12-02 10:40:00 | role in regulating the mitochondrial fission machinery | 28646508 |
| 2017-07-01 12:19:00 | The exogenous expression of hepatic stimulator substance (HSS was renamed augmenter of liver regeneration ALR) protected the liver from steatosis in mice with nonalcoholic steatohepatitis. | 27991906 |
| Type | IDs |
|---|---|
| Synonymous | Alr, ERV1 |
| Gene |
UniProtKB-ID:
ALR_MOUSE,
A0A3Q4EGL6_MOUSE
UniprotKB:
P56213,
A0A3Q4EGL6
UniParc:
UPI0005AB9E01,
UPI00000E732C
EMBL:
AC154566,
AB041561,
AF148688,
BC023941,
CH466606,
AK146579,
U40494
Ensembl:
ENSMUSG00000040888
KO:
mmu:11692
|
| Nucleutide sequences |
EMBL-CDS:
BAA95045.1,
AAD36987.1,
AAH23941.1,
BAE27275.1,
EDL22354.1,
AAD10339.1
Gene_ORFName:
MNCb-0663
Ensembl_TRS:
ENSMUST00000046839,
ENSMUST00000234197,
ENSMUST00000234520,
ENSMUST00000234235
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000049186,
ENSMUSP00000157329,
ENSMUSP00000157116,
ENSMUSP00000157249
RefSeq:
NP_001365968.1,
NP_075527.2,
NP_001365967.1,
XP_036016164.1
|
| Others |
UniRef100:
UniRef100_P56213,
UniRef100_A0A3Q4EGL6
UniRef90:
UniRef90_P56213
UniRef50:
UniRef50_P55789
UniGene:
Mm.28124
CCDS:
CCDS28492.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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