| Type | Description |
|---|---|
| Definition | arachidonate 5-lipoxygenase activating protein |
| Date | Results | Publications |
|---|---|---|
| 2019-04-13 11:09:00 | Within the endothelial population, cells that transition from haemogenic endothelial to erythro-myeloid progenitors specifically express Alox5 and its co-factor Alox5ap, which control leukotriene production. Functional assays using mouse embryonic stem cells demonstrate that leukotrienes promote haematopoietic progenitor cell generation. | 29311656 |
| 2017-06-10 12:44:00 | ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance | 27207555 |
| 2016-12-17 10:09:00 | Data indicate that a single amino acid mutation was sufficient to reverse the speciation observed in wild type 5-Lipoxygenase activating protein (FLAP). | 27129215 |
| 2015-01-24 11:08:00 | BRP-7 potently suppresses leukotriene biosynthesis by interacting with FLAP in mouse peritonitis model. | 24641614 |
| 2014-06-07 12:12:00 | FLAP regulates phosphorylation of tau protein via modulating GSK-3beta activity. | 24301651 |
| Type | IDs |
|---|---|
| Synonymous | Flap |
| Gene |
UniProtKB-ID:
AL5AP_MOUSE
UniprotKB:
P30355
UniParc:
UPI0000029A3E
EMBL:
M96554,
AK004002,
BC026209
Ensembl:
ENSMUSG00000060063
KO:
mmu:11690
|
| Nucleutide sequences |
EMBL-CDS:
AAH26209.1,
BAB23117.1,
AAA37632.1
Ensembl_TRS:
ENSMUST00000071130
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000071130
RefSeq:
NP_033793.1,
NP_001295391.1
|
| Others |
UniRef100:
UniRef100_P30355
UniRef90:
UniRef90_P30355
UniRef50:
UniRef50_P20292
UniGene:
Mm.19844
CCDS:
CCDS39407.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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