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11689 Alox5

11689

Alox5

arachidonate 5-lipoxygenase

protein-coding

Mus musculus

基因描述

Type Description
Definition arachidonate 5-lipoxygenase

研究结论

Date Results Publications
2020-10-10 12:58:00 Functional Characterization of Knock-In Mice Expressing a 12/15-Lipoxygenating Alox5 Mutant Instead of the 5-Lipoxygenating Wild-Type Enzyme. 31642348
2020-09-12 16:00:00 Leukotriene Synthesis Is Critical for Medulloblastoma Progression. 31300449
2019-08-03 12:43:00 that 5-lipoxygenase directly modulates tau phosphorylation at the same epitopes via the cdk5 kinase pathway 29106033
2019-07-06 10:34:00 Data show that the 5-Lipoxygenase knockout mice (5-LO(-/-) wounds had diminished mRNA expression in the skin lesions. 28965882
2019-04-13 11:09:00 Within the endothelial population, cells that transition from haemogenic endothelial to erythro-myeloid progenitors specifically express Alox5 and its co-factor Alox5ap, which control leukotriene production. Functional assays using mouse embryonic stem cells demonstrate that leukotrienes promote haematopoietic progenitor cell generation. 29311656

名称对应

Type IDs
Synonymous 5-LO, 5-LOX, 5LO, 5LX, AI850497, F730011J02
Gene
UniProtKB-ID: LOX5_MOUSE
UniprotKB: P48999
UniParc: UPI00001F41CF
EMBL: AK137481, BC139102, AK171413, L42198, BC141213
Ensembl: ENSMUSG00000025701
KO: mmu:11689
Nucleutide sequences
EMBL-CDS: BAE23373.1, AAI39103.1, AAI41214.1, AAC37673.1, BAE42439.1
Ensembl_TRS: ENSMUST00000026795
Protein sequencees
Ensembl_PRO: ENSMUSP00000026795
RefSeq: XP_036021653.1, NP_033792.1
Others
UniRef100: UniRef100_P48999
UniRef90: UniRef90_P09917-2
UniRef50: UniRef50_P09917
UniGene: Mm.41072
CCDS: CCDS20452.1

全选

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研究热度

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