| Type | Description |
|---|---|
| Definition | arachidonate 8-lipoxygenase |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:11:00 | Our findings, for the first time, strongly indicate that 1a may serve as a potent and promising cardioprotective agent in treatment of ischemia-reperfusion (I/R) injury, at least partially through targeting 12/15-LOX-2. | 31362020 |
| 2017-05-20 14:00:00 | 15-LOX-2 is distributed at the plasma membrane when cells are stimulated by the addition Ca(2+) ionophore and that cellular localization is dependent upon the presence of a putative membrane insertion loop. | 27435673 |
| 2013-05-04 10:47:00 | Knockdown of mouse Alox15b in vivo decreased plaque lipid content and markers of inflammation. | 22912809 |
| 2010-08-23 11:58:00 | 15-LOX2 expression in mouse prostate leads to hyperplasia and also induces cell senescence. | 20514017 |
| 2010-01-21 00:00:00 | 8S-LOX plays a role as a prodifferentiating, antitumorigenic, and tumor suppressing gene in mouse skin carcinogenesis. | 15558016 |
| Type | IDs |
|---|---|
| Synonymous | 15-LOX-2, 15-LOX-B, 8-LOX, 8S-LOX, Alox15b |
| Gene |
UniProtKB-ID:
ALOX8_MOUSE
UniprotKB:
O35936
UniParc:
UPI0000001956
EMBL:
U93277,
AL645527,
Y14696,
AK028724,
BC015253
Ensembl:
ENSMUSG00000020891
KO:
mmu:11688
|
| Nucleutide sequences |
EMBL-CDS:
AAC53356.1,
BAC26085.1,
CAA75003.1,
AAH15253.1
Ensembl_TRS:
ENSMUST00000021262
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021262
RefSeq:
NP_033791.1
|
| Others |
UniRef100:
UniRef100_O35936
UniRef90:
UniRef90_O35936
UniRef50:
UniRef50_O15296
UniGene:
Mm.289672
CCDS:
CCDS24886.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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