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116873 Stim2

116873

Stim2

stromal interaction molecule 2

protein-coding

Mus musculus

基因描述

Type Description
Definition stromal interaction molecule 2

研究结论

Date Results Publications
2020-10-24 13:57:00 Orai1 inhibitor STIM2beta regulates myogenesis by controlling SOCE dependent transcriptional factors. 31346235
2020-07-04 10:23:00 These data indicate that STIM1 and STIM2 have differential roles in the production of IL-4, which are stimulus dependent. Furthermore, these results illustrate the vital role of STIM2 in basophils, which is often considered to be less important than STIM1. 30967512
2020-01-04 10:43:00 mice deficient in both Stim1 and Stim2 in T cells (conditional double knockout [cDKO]) developed lymphoproliferative disorders and skin inflammation with a concomitant increase in serum IgG1 and IgE levels. 30910863
2019-10-26 12:08:00 Results indicate that preformed clusters of STIM and ORAI1 enable local Ca(2+) entry events in unstimulated cells. Upon TCR activation, NAADP-evoked Ca(2+) release through RYR1, in coordination with Ca(2+) entry through ORAI1 and STIM, rapidly increases the number of Ca(2+) microdomains, thereby initiating spread of Ca(2+) signals deeper into the cytoplasm to promote full T cell activation. 30563862
2019-08-24 11:47:00 data show that loss of SOCE in enamel cells has substantial detrimental effects on gene expression, cell function, and the mineralization of dental enamel 28352661

名称对应

Type IDs
Gene
UniProtKB-ID: STIM2_MOUSE, A5CVE4_MOUSE
UniprotKB: P83093, A5CVE4
UniParc: UPI0000E4450A
EMBL: BC043455, AK173183, AF328907, AM712359
Ensembl: ENSMUSG00000039156
KO: mmu:116873
Nucleutide sequences
EMBL-CDS: BAD32461.1, AAK82339.1, AAH43455.1, CAN36430.1
Ensembl_TRS: ENSMUST00000117661
Protein sequencees
Ensembl_PRO: ENSMUSP00000113174
RefSeq: NP_001074572.2, NP_001350277.1, NP_473424.2
Others
UniRef100: UniRef100_P83093
UniRef90: UniRef90_P83093
UniRef50: UniRef50_P83093
UniGene: Mm.265985
CCDS: CCDS39089.2

全选

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研究热度

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