| Type | Description |
|---|---|
| Definition | arachidonate 12-lipoxygenase, 12R type |
| Date | Results | Publications |
|---|---|---|
| 2014-04-19 11:52:00 | Loss-of-function mutations in the LOX genes ALOX12B and ALOXE3 have been found to represent the second most common cause of autosomal recessive congenital ichthyosis. [review] | 23954555 |
| 2010-01-21 00:00:00 | The 12R-LOX-eLOX-3 pathway plays a key role in the process of epidermal barrier acquisition by affecting lipid metabolism, as well as protein processing. | 17403930 |
| 2010-01-21 00:00:00 | Alox12b-deficient mouse skin transplants have an ichthyosiform phenotype | 19122646 |
| Type | IDs |
|---|---|
| Synonymous | 12R-LOX, Aloxe2, e-LOX2 |
| Gene |
UniProtKB-ID:
LX12B_MOUSE,
Q2KHL0_MOUSE
UniprotKB:
O70582,
Q2KHL0
UniParc:
UPI0000023F96
EMBL:
BC113149,
AF059251,
Y14334
Ensembl:
ENSMUSG00000032807
KO:
mmu:11686
|
| Nucleutide sequences |
EMBL-CDS:
CAA74714.1,
AAC79681.1,
AAI13150.1
Ensembl_TRS:
ENSMUST00000036424
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035250
RefSeq:
NP_033789.1
|
| Others |
UniRef100:
UniRef100_O70582
UniRef90:
UniRef90_O70582
UniRef50:
UniRef50_O75342
UniGene:
Mm.340329
CCDS:
CCDS24885.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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