| Type | Description |
|---|---|
| Definition | anaplastic lymphoma kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | ALK-transformed mature T lymphocytes restore early thymus progenitor features. | 33141118 |
| 2020-10-24 14:02:00 | Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice. | 31526103 |
| 2018-10-13 11:44:00 | Anaplastic lymphoma kinase (ALK) is a novel regulator of NLRP3 inflammasome activation in macrophages. Mechanically, ALK-mediated NF-kappaB activation was required for the priming step of NLRP3 upregulation, whereas ALK-mediated lipid peroxidation contributed to the sensing step of NLRP3-NEK7 complex formation. | 29723525 |
| 2018-05-26 11:10:00 | NLRR1 appears to be an extracellular negative regulator of ALK signalling in neuroblastoma and neuronal development. | 27604320 |
| 2018-03-17 11:51:00 | These data support an important role for the p55gamma subunit of PI3K in ALK-induced cell migration during brain development | 27322022 |
| Type | IDs |
|---|---|
| Synonymous | CD246, Tcrz |
| Gene |
UniProtKB-ID:
ALK_MOUSE
UniprotKB:
P97793
UniParc:
UPI0000355437
EMBL:
AC154458,
D83002,
AC154602,
AC122746,
AC154659,
AC155242,
AC151265
Ensembl:
ENSMUSG00000055471
KO:
mmu:11682
|
| Nucleutide sequences |
EMBL-CDS:
BAA11673.1
Ensembl_TRS:
ENSMUST00000086639
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000083840
RefSeq:
NP_031465.2,
XP_036016162.1,
XP_036016161.1
|
| Others |
UniRef100:
UniRef100_P97793
UniRef90:
UniRef90_P97793
UniRef50:
UniRef50_Q9UM73
UniGene:
Mm.311854
CCDS:
CCDS37688.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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