| Type | Description |
|---|---|
| Definition | forkhead box N4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:21:00 | Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis.In early embryonic retinas, Foxn4 inactivation causes down-regulation of photoreceptor marker genes and decreased photoreceptor generation but increased RGC production, whereas its overexpression has the opposite effect. | 32071204 |
| 2014-03-15 10:07:00 | the mosaic expression of Foxn4 and proneural factors may serve as the trigger to initiate asymmetric Dll4-Notch and subsequent BMP/TGFbeta signaling events required for neuronal diversity in the V2 domain. | 24257627 |
| 2012-09-15 10:56:00 | Mouse Foxn4 transfection reduced by 2.7-fold the basal level of Tbx2 promoter transcription, but deletion of the AD domain increased transcription showing that this domain might be a transregulatory domain. | 21701787 |
| 2012-05-12 11:11:00 | Foxn4 has an intrinsic activity to suppress the alternative photoreceptor cell fates of early retinal progenitors by selectively activating Dll4-Notch signaling. | 22323600 |
| 2011-10-08 11:05:00 | Foxn4 may have a non-cell-autonomous role critical for alveologenesis during lung development. | 21438071 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
FOXN4_MOUSE
UniprotKB:
Q8K3Q3
UniParc:
UPI0000025E30
EMBL:
AY039039,
BC092242,
BC130222,
AF323488
Ensembl:
ENSMUSG00000042002
KO:
mmu:116810
|
| Nucleutide sequences |
EMBL-CDS:
AAL06288.1,
AAK72101.1,
AAI30223.1,
AAH92242.1
Ensembl_TRS:
ENSMUST00000044790
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000047951
RefSeq:
XP_006530185.1,
XP_006530184.1,
XP_011246462.1,
NP_683737.2
|
| Others |
UniRef100:
UniRef100_Q8K3Q3
UniRef90:
UniRef90_Q8K3Q3
UniRef50:
UniRef50_Q8K3Q3
UniGene:
Mm.17709
CCDS:
CCDS19562.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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