| Type | Description |
|---|---|
| Definition | aldo-keto reductase family 1, member B3 (aldose reductase) |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 12:36:00 | AR deficiency accentuates the pathological effects of transverse aortic constriction. | 29627295 |
| 2017-03-11 12:26:00 | modulation of macrophage metabolism by inhibition of AR might represent a novel strategy to modulate host defense responses and to modify metabolism to promote macrophage hypertrophy and phagocytosis under inflammatory conditions | 28111134 |
| 2016-10-08 11:17:00 | Aldose reductase acts as a switch which can regulate microglia by polarizing cells after spinal cord injury. | 25520004 |
| 2016-09-03 11:38:00 | AR overexpression elevates retinal microglia activation in retina. | 27033597 |
| 2014-06-14 10:58:00 | Aldose reductase contributes to diabetes-mediated mitochondrial dysfunction and damage through the activation of p53. | 24474649 |
| Type | IDs |
|---|---|
| Synonymous | ALR2, AR, Ahr-1, Ahr1, Akr1b1, Aldor1, Aldr1 |
| Gene |
UniProtKB-ID:
ALDR_MOUSE,
Q3UDY1_MOUSE
UniprotKB:
P45376,
Q3UDY1
UniParc:
UPI0000020B9C
EMBL:
BC021655,
U89142,
U89147,
U93231,
U89149,
AB016665,
U89145,
D32250,
AK153949,
U89140,
AK150197,
U89146,
U89143,
U89148,
U93230,
BC004725,
U89150,
AK149861,
U89144,
AK164682,
AK139250,
U29152,
L39795
Ensembl:
ENSMUSG00000001642
KO:
mmu:11677
|
| Nucleutide sequences |
EMBL-CDS:
AAA62176.1,
AAH04725.1,
AAD32300.1,
BAA06980.1,
AAA69958.1,
BAA76413.1,
AAH21655.1,
AAC13358.1,
BAE37874.1,
BAE23933.1,
BAE29130.1,
BAE29373.1,
BAE32272.1
Ensembl_TRS:
ENSMUST00000102980
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000100045
RefSeq:
NP_033788.3
|
| Others |
UniRef100:
UniRef100_P45376
UniRef90:
UniRef90_P07943
UniRef50:
UniRef50_P07943
UniGene:
Mm.451,
Mm.389126
CCDS:
CCDS19990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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