| Type | Description |
|---|---|
| Definition | SH3 domain containing GRB2 like 2, endophilin A1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-14 11:45:00 | A potential role for endophilin 1 in Abetainduced postsynaptic dysfunction has been identified, indicating a possible direction for the prevention of postsynaptic dysfunction in cognitive impairment and suggesting that endophilin may be a potential target for the clinical treatment of Alzheimer's disease. | 31059028 |
| 2018-06-23 11:40:00 | Together, these observations suggest that while endophilin helps shape endocytic tubules and recruit dynamin to endocytic sites, it can also block membrane fission when present in excess by inhibiting inter-dynamin interactions. | 28933693 |
| 2016-12-17 11:00:00 | These data suggested a role of EndoII in protecting BASMCs apoptosis induced by H2O2, possibly by inhibiting the addressing of Bax to mitochondria. Targeting on EndoII may be a new strategy to treat apoptosis-associated diseases. | 26854628 |
| 2014-07-12 10:17:00 | We find that the phosphomimetic mutation S75D favors vesicle formation by inhibiting this conformational switch, acting to regulate endophilin A1-mediated curvature. | 24778241 |
| 2013-08-10 11:47:00 | a coarse-grained model was used to study various membrane remodeling scenarios induced by endophilin N-terminal helix and Bin/amphiphysin/Rvs domains. | 23442862 |
| Type | IDs |
|---|---|
| Synonymous | Sh3d2a, Sh3p4 |
| Gene |
UniProtKB-ID:
SH3G2_RAT
UniprotKB:
O35179
UniParc:
UPI00006027E6
EMBL:
AC112121,
AF009603,
AI044966
Ensembl:
ENSRNOG00000006761
KO:
rno:116743
|
| Nucleutide sequences |
EMBL-CDS:
AAC14883.1
Ensembl_TRS:
ENSRNOT00000008999
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000008999
RefSeq:
XP_006238421.1,
XP_017448613.1,
NP_446387.1
|
| Others |
UniRef100:
UniRef100_O35179
UniRef90:
UniRef90_O35179
UniRef50:
UniRef50_Q99961
UniGene:
Rn.10787
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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