| Type | Description |
|---|---|
| Definition | aldehyde dehydrogenase family 1, subfamily A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:03:00 | ALDH1A1 regulates postsynaptic mu-opioid receptor expression in dorsal striatal projection neurons and mitigates dyskinesia through transsynaptic retinoic acid signaling. | 30837649 |
| 2020-07-04 12:49:00 | A reporter construct for self-renewing cancer stem cells (CSCs), based on ALDH1A1 expression. Oral cancer cells harboring ALDH1A1-DsRed2 were used to screen inhibitors that target CSCs. | 31401066 |
| 2019-06-08 11:55:00 | These results suggest that retinoic acids produced by Aldh1a1 in the neural retina directs dorsal choroidal vascular development via Sox9 upregulation in the dorsal retinal pigment epithelial cells to enhance retinal pigment epithelial-derived VEGF secretion. | 29609731 |
| 2019-03-09 11:07:00 | Finally, ATRA replacement suppressed 15-PGDH inhibition-induced tumor progression in KC mice, and ATRA treatment attenuated Aldh1 activity in tumor cells isolated from the pancreas of 15-Pgdh(-/-) KC mice. These findings provide evidence that 15-PGDH inhibition enhances KRAS-driven tumor progression via ATRA depletion in the pancreas. Therefore, ATRA replacement could be a potential strategy for PDAC treatment. | 30250298 |
| 2017-06-03 12:11:00 | Data indicate involvement of non-POU domain-containing octamer-binding protein (NONO)/paraspeckle protein component 1 (PSPC1)-aldehyde dehydrogenase 1 (NONO/PSPC1-ALDH1A1) in the modulation of Sertoli cells (SCs) response to mono-(2-ethylhexyl) phthalate (MEHP) challenge. | 28117896 |
| Type | IDs |
|---|---|
| Synonymous | ALDH-E1, ALHDII, Ahd-2, Ahd2, Aldh1, Aldh1a2, E1, Raldh1 |
| Gene |
UniProtKB-ID:
AL1A1_MOUSE
UniprotKB:
P24549
UniParc:
UPI00001B21EC
EMBL:
BC054386,
S75713,
BC044729,
M74571,
S77047,
M74570
Ensembl:
ENSMUSG00000053279
KO:
mmu:11668
|
| Nucleutide sequences |
EMBL-CDS:
AAB32754.2,
AAA37202.1,
AAA37203.1,
AAH44729.1,
AAH54386.1
Ensembl_TRS:
ENSMUST00000087638,
ENSMUST00000225337
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000153410,
ENSMUSP00000084918
RefSeq:
NP_001348435.1,
NP_001348434.1,
NP_001348432.1,
NP_038495.2,
NP_001348433.1
|
| Others |
UniRef100:
UniRef100_P24549
UniRef90:
UniRef90_P24549
UniRef50:
UniRef50_P00352
UniGene:
Mm.250866
CCDS:
CCDS29695.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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