| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 10:49:00 | data support the notion that p38-MAPK activation after myocardial stretch restricts the SFR by limiting ERK1/2-p90RSK phosphorylation, and consequently NHE-1 phosphorylation/activity, through a mechanism that involves DUSP6 up-regulation. | 30816666 |
| 2017-05-20 13:58:00 | these results suggest that FSH-stimulated ERK activation in granulosa cells requires the inactivation of MKP3(DUSP6). | 27422819 |
| 2016-02-06 11:46:00 | The expression of DUSP6 and DUSP7 is mediated by ERK1/ERK2 activity in microglia. | 26435497 |
| 2014-12-27 12:24:00 | data demonstrate THAT MKP-3 has differential substrate preference in astrocytes compared to other cells types, since it preferentially dephosphorylated p-JNK over p-ERK. | 24861519 |
| 2014-09-06 10:45:00 | The MKP3 expression reduces neurotransmitter release by decreasing the expression of cav1.2. Because MKP3 is increased when neuronal activity is elevated, this process could play a role in regulating neurotransmitter homeostasis. | 23337371 |
| Type | IDs |
|---|---|
| Synonymous | Mkp3 |
| Gene |
UniProtKB-ID:
DUS6_RAT
UniprotKB:
Q64346
UniParc:
UPI0000129962
EMBL:
U42627,
BC087003,
X94185
Ensembl:
ENSRNOG00000023896
KO:
rno:116663
|
| Nucleutide sequences |
EMBL-CDS:
AAH87003.1,
AAB06202.1,
CAA63895.1
Ensembl_TRS:
ENSRNOT00000037844
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000032969
RefSeq:
NP_446335.1
|
| Others |
UniRef100:
UniRef100_Q64346
UniRef90:
UniRef90_Q16828
UniRef50:
UniRef50_Q16828
UniGene:
Rn.4313
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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