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11666 Abcd1

11666

Abcd1

ATP-binding cassette, sub-family D (ALD), member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family D (ALD), member 1

研究结论

Date Results Publications
2019-12-07 11:48:00 Combined absence of ABCD1 and ABCD2 proteins resulted in the accumulation of very long-chain fatty acids in murine BV-2 cells. 30769094
2019-01-19 10:37:00 These results show that ABCD1-deficiency causes metabolic alternation of long-chain fatty acids and VLCFA. Moreover, our results imply a molecular mechanism for the incorporation of saturated or monounsaturated VLCFA into the sn-1 position of phospholipids, and also indicate that the distribution of phospholipids with VLCFA may correlate with the development of X-ALD. 29469952
2017-07-15 10:19:00 ABCD1 and its homolog ABCD2 exist mainly as homotetramers in the peroxisomal membrane 28258215
2016-08-27 10:04:00 during the active myelination phase the microsomal fatty acid elongation activity is stimulated in abcd1-deficient mice 26108493
2016-04-09 10:32:00 Deletion of AMPKalpha1 in the mixed glial cells of Abcd1-KO mice induced spontaneous mitochondrial dysfunction 25861159

名称对应

Type IDs
Synonymous ALDP, Ald, Aldgh
Gene
UniProtKB-ID: ABCD1_MOUSE
UniprotKB: P48410
UniParc: UPI0000001909
EMBL: Z33637, AF133093, BC079840, AJ009991, BC011273, AK088792
Ensembl: ENSMUSG00000031378
KO: mmu:11666
Nucleutide sequences
EMBL-CDS: CAA83917.1, BAC40574.1, AAH11273.1, CAA08935.1, AAH79840.1
Ensembl_TRS: ENSMUST00000002084
Protein sequencees
Ensembl_PRO: ENSMUSP00000002084
RefSeq: NP_031461.1
Others
UniRef100: UniRef100_P48410
UniRef90: UniRef90_P33897
UniRef50: UniRef50_P33897
UniGene: Mm.365
CCDS: CCDS30210.1

全选

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研究热度

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