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116647 Nlgn1

116647

Nlgn1

neuroligin 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition neuroligin 1

研究结论

Date Results Publications
2021-02-13 13:23:00 Alternative splicing at neuroligin site A regulates glycan interaction and synaptogenic activity. 32915137
2019-06-29 10:37:00 Results showed that in pyramidal and interneurons, neuroligin 1 and neuroligin 3 were involved in excitatory synapse formation, and neuroligin 2 in GABAergic synapse formation. 30790215
2019-03-30 10:16:00 To characterize the possible contribution of NLGN1 to inflammatory pain, the present study analyzed the changes of NLGN1 expression after intraplantar injection of complete Freund's adjuvant (CFA). Our data revealed an activity-dependent recruitment of NLGN1 into synapses, which was essential for NMDAR hyperfunction and pain hypersensitivity. 30049666
2018-10-27 11:58:00 downregulation of spinal neuroligin1 expression may ameliorate postoperative pain through inhibiting neuroligin1/PSD-95 interaction and synaptic targeting of GluA1 subunit. 29592780
2018-05-26 10:11:00 Following endoplasmic reticulum exit, the AMPA-type glutamate receptor GluA1 and neuroligin 1 undergo spatially restricted entry into the dendritic secretory pathway and accumulate in recycling endosomes (REs) located in dendrites and spines before reaching the plasma membrane. 28875935

名称对应

Type IDs
Gene
UniProtKB-ID: NLGN1_RAT
UniprotKB: Q62765
UniParc: UPI000019C401, UPI000019C402, UPI000019C403, UPI00000E5903
EMBL: U22952
Ensembl: ENSRNOG00000032576
KO: rno:116647
Nucleutide sequences
EMBL-CDS: AAA85720.1
Ensembl_TRS: ENSRNOT00000092660
Protein sequencees
Ensembl_PRO: ENSRNOP00000075793
RefSeq: XP_017446076.1, XP_008759112.1, XP_017446074.1, XP_017446078.1, XP_017446077.1, XP_017446079.1, NP_446320.1, XP_017446072.1, XP_017446073.1, XP_017446075.1
Others
UniRef100: UniRef100_Q62765
UniRef90: UniRef90_Q62765
UniRef50: UniRef50_Q62765
UniGene: Rn.10173

全选

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研究热度

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