| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 4E binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 15:12:00 | These results indicate that a low-protein diet increases the amount of 4E-BP1, leading to TG accumulation in rat liver. We thus conclude that 4E-BP1 plays an important role in inducing hepatic steatosis under protein deprivation. | 32208000 |
| 2019-05-25 10:12:00 | In an anterior cruciate ligament transection model of osteoarthritis, 4E-BP1 inactivation precedes cartilage degeneration and increased expression of pathogenic proteases in cartilage. | 29761560 |
| 2017-08-19 12:03:00 | FGF signaling differentially impacts protein synthesis through either stimulation or repression, in a cell-type-dependent manner, with 4E-BP1 being a key player. | 27313212 |
| 2017-02-18 11:05:00 | Suggest that 4-nonylphenol stimulates Sertoli cell autophagy and inhibits mTOR-p70S6K/4EBP1 activity through AMPK activation. | 28041982 |
| 2016-12-17 10:44:00 | mTOR plays an important role in spermatogenesis by regulating p70s6k activation; 4e-bp1 is either directly or indirectly regulated by PI3K | 26706460 |
| Type | IDs |
|---|---|
| Synonymous | PHAS-I |
| Gene |
UniProtKB-ID:
4EBP1_RAT
UniprotKB:
Q62622
UniParc:
UPI00000E729C
EMBL:
U05014
Ensembl:
ENSRNOG00000012582
KO:
rno:116636
|
| Nucleutide sequences |
EMBL-CDS:
AAA86938.1
Ensembl_TRS:
ENSRNOT00000016885
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016885
RefSeq:
NP_446309.1
|
| Others |
UniRef100:
UniRef100_Q62622
UniRef90:
UniRef90_Q13541
UniRef50:
UniRef50_Q13541
UniGene:
Rn.11161
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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