| Type | Description |
|---|---|
| Definition | S100 calcium binding protein A8 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 10:40:00 | Establish S100A8 transgenic rats to elucidate role as a regulator in acute inflammation. | 28913572 |
| 2018-03-10 10:05:00 | The results obtained in the present study demonstrate for the first time that S100A8 as well as MyD88 and NF-B are activated by T3 and that these molecules are directly involved in the thyroid hormone-induced cardiac hypertrophic response. These data suggest that one of the mechanisms underlying T3-dependent cardiac hypertrophy/failure may involve the activation of an inflammatory pathway. | 28161820 |
| 2017-09-16 13:23:00 | Recombinant rat r-S100A8 bound to r-CD68. The expression levels of S100A8 were significantly suppressed after the macrophages had been treated with an anti-CD68 antibody. Small interfering CD68 also significantly suppressed activation of macrophages through an autocrine pathway by r-S100A8. | 27312849 |
| 2017-06-24 10:27:00 | results support S100A8 as a novel therapeutic target to control ASM contraction in asthma | 28088518 |
| 2017-02-18 10:49:00 | vagus nerve electrical stimulation may produce a protective effect on septic shock in rats by decreasing the production of S100A8. | 27035526 |
| Type | IDs |
|---|---|
| Synonymous | Mrp8 |
| Gene |
UniProtKB-ID:
S10A8_RAT
UniprotKB:
P50115
UniParc:
UPI000019BC84
EMBL:
L18891
Ensembl:
ENSRNOG00000011557
KO:
rno:116547
|
| Nucleutide sequences |
EMBL-CDS:
AAA41637.1
Ensembl_TRS:
ENSRNOT00000015473
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015473
RefSeq:
XP_006232627.1,
NP_446274.2
|
| Others |
UniRef100:
UniRef100_P50115
UniRef90:
UniRef90_P50115
UniRef50:
UniRef50_P50115
UniGene:
Rn.31839
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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