| Type | Description |
|---|---|
| Definition | TIMP metallopeptidase inhibitor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:34:00 | Secretome Analysis of Factors Fostering Oligodendroglial Differentiation of In Vivo. | 32570968 |
| 2020-05-23 11:39:00 | MMP9 and TIMP-1 may have a role in tissue remodeling in a rat model of heart failure | 31099017 |
| 2019-09-21 10:51:00 | The present study is the first to demonstrate that cold exposure exacerbates imbalance between MMP-9 and TIMP-1 by activating the RAS, which may be critical in the initiation of stroke during chronic hypertension | 31200003 |
| 2019-08-17 10:42:00 | These data provide a previously uncharacterized trophic action of TIMP-1 to regulate oligodendrocyte maturation via a CD63/beta1-integrin/Akt pathway mechanism. | 30121936 |
| 2019-07-06 10:51:00 | Overexpression of prolyl-hydroxylase 2 (PHD2) transgene, a predominant isoform of PHDs in renal tubules, to reduce HIF-1alpha level significantly attenuated albumin-induced increases in TIMP-1 and collagen-I levels. These results suggest that albumin-induced oxidative stress inhibits PHD activity to accumulate HIF-1alpha, which mediates albumin-induced profibrotic effects in renal tubular cells | 29158549 |
| Type | IDs |
|---|---|
| Synonymous | TIMP-1, Timp |
| Gene |
UniProtKB-ID:
TIMP1_RAT
UniprotKB:
P30120
UniParc:
UPI0000136F91
EMBL:
U16022,
U06179,
BC099821,
L29512,
L31883,
AY550026
Ensembl:
ENSRNOG00000010208
KO:
rno:116510
|
| Nucleutide sequences |
EMBL-CDS:
AAS55641.1,
AAH99821.1,
AAA51653.1,
AAB08483.1,
AAA85780.1,
AAA85373.1
Ensembl_TRS:
ENSRNOT00000013745
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000013745
RefSeq:
XP_006256670.1,
NP_446271.1
|
| Others |
UniRef100:
UniRef100_P30120
UniRef90:
UniRef90_P30120
UniRef50:
UniRef50_P30120
UniGene:
Rn.25754
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员