Type | Description |
---|---|
Definition | F2R like thrombin or trypsin receptor 3 |
Date | Results | Publications |
---|---|---|
2015-08-08 10:39:00 | increased thrombin activity 6 to 24 hours after germinal matrix hemorrhage, and PAR-1, PAR-4, inhibition normalized cyclooxygenase-2, and mammalian target of rapamycin by 72 hours. | 25931468 |
2014-06-21 10:53:00 | activation of PAR4 upregulates the expression of CGRP mRNA and protein levels in dorsal root ganglion neurons | 24105611 |
2011-07-29 16:02:00 | PAR1 and PAR3 could be involved in thrombin-modulated initiation of post-ischemic inflammation and PAR4 may be associated with neuronal degeneration. (Protease-activated receptor 1, 3, 4) | 16403464 |
2011-01-08 10:31:00 | PAR1 and PAR4 are functionally expressed in large myelinated fibre neurons, and are also expressed in small nociceptors of the peptidergic subclass, where they are able to potentiate TRPV1 activity. | 20875131 |
2010-04-12 12:10:00 | in normal rat knee joints, PAR4 activation increases joint primary afferent activity in response to mechanical stimuli. This PAR4-induced sensitization is TRPV1-independent but involves B2 receptor activation, suggesting a role for kinins in this process | 19889854 |
Type | IDs |
---|---|
Synonymous | PAR4 |
Gene |
UniProtKB-ID:
PAR4_RAT
UniprotKB:
Q920E0
UniParc:
UPI000013131A
EMBL:
AF269246,
AF310216
KO:
rno:116498
|
Nucleutide sequences |
EMBL-CDS:
AAL26790.1,
AAK58604.2
|
Protein sequencees |
RefSeq:
NP_446260.1
|
Others |
UniRef100:
UniRef100_Q920E0
UniRef90:
UniRef90_O88634
UniRef50:
UniRef50_O88634
UniGene:
Rn.81079
|
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