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116498 F2rl3

116498

F2rl3

F2R like thrombin or trypsin receptor 3

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition F2R like thrombin or trypsin receptor 3

研究结论

Date Results Publications
2015-08-08 10:39:00 increased thrombin activity 6 to 24 hours after germinal matrix hemorrhage, and PAR-1, PAR-4, inhibition normalized cyclooxygenase-2, and mammalian target of rapamycin by 72 hours. 25931468
2014-06-21 10:53:00 activation of PAR4 upregulates the expression of CGRP mRNA and protein levels in dorsal root ganglion neurons 24105611
2011-07-29 16:02:00 PAR1 and PAR3 could be involved in thrombin-modulated initiation of post-ischemic inflammation and PAR4 may be associated with neuronal degeneration. (Protease-activated receptor 1, 3, 4) 16403464
2011-01-08 10:31:00 PAR1 and PAR4 are functionally expressed in large myelinated fibre neurons, and are also expressed in small nociceptors of the peptidergic subclass, where they are able to potentiate TRPV1 activity. 20875131
2010-04-12 12:10:00 in normal rat knee joints, PAR4 activation increases joint primary afferent activity in response to mechanical stimuli. This PAR4-induced sensitization is TRPV1-independent but involves B2 receptor activation, suggesting a role for kinins in this process 19889854

名称对应

Type IDs
Synonymous PAR4
Gene
UniProtKB-ID: PAR4_RAT
UniprotKB: Q920E0
UniParc: UPI000013131A
EMBL: AF269246, AF310216
KO: rno:116498
Nucleutide sequences
EMBL-CDS: AAL26790.1, AAK58604.2
Protein sequencees
RefSeq: NP_446260.1
Others
UniRef100: UniRef100_Q920E0
UniRef90: UniRef90_O88634
UniRef50: UniRef50_O88634
UniGene: Rn.81079

全选

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研究热度

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