| Type | Description |
|---|---|
| Definition | family with sequence similarity 129 member A |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:46:00 | MRNA and protein expression of FAM129A were negatively regulated by miR-135a. | 31729558 |
| 2020-03-07 12:43:00 | Our data suggest that, in normal thyroid cells, FAM129A induces autophagy in order to maintain cell homeostasis and provide substrates under starvation conditions. Instead, in thyroid cancer cells, decreased autophagy may help the cells to overcome cell death. FAM129A regulates autophagy in a cell- and/or context-dependent manner. | 30400008 |
| 2020-02-01 13:09:00 | One of the canonical Unfolded protein response branches, through ATF4 and its target gene FAM129A, is required for Prostate cancer growth and thus may serve as a novel therapeutic target. | 31312022 |
| 2020-01-18 11:30:00 | Silencing of Niban in HK-2 cells not only increased the AngII- and endoplasmic reticulum stress-induced apoptosis, but also promoted the expression of caspase 8, caspase 9, Bip, and Chop, suggesting that Niban protein is involved in apoptosis regulation in HK-2 cells, and most likely via caspase-dependent pathway. | 31163002 |
| 2019-09-21 10:19:00 | We have shown that FAM129A is associated with variation in clinical asthma steroid responsiveness and that FAM129A modulates steroid responsiveness in lung epithelial cells. | 29410046 |
| Type | IDs |
|---|---|
| Synonymous | C1orf24, GIG39, NIBAN |
| Gene |
UniProtKB-ID:
NIBA1_HUMAN
UniprotKB:
Q9BZQ8
UniParc:
UPI00000375B3
EMBL:
AB050477,
AL109956,
AY550972,
AL096819,
AL136086,
AF288391,
BC030531,
AK074139,
AL109865,
AK022527
Ensembl:
ENSG00000135842
KO:
hsa:116496
|
| Nucleutide sequences |
EMBL-CDS:
BAB17230.1,
AAH30531.1,
AAG60611.1,
BAB84965.1,
AAT52218.1,
BAB14079.1
Gene_ORFName:
GIG39
Ensembl_TRS:
ENST00000367511
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356481
RefSeq:
XP_011507443.1,
XP_011507442.1,
NP_443198.1
|
| Others |
UniRef100:
UniRef100_Q9BZQ8
UniRef90:
UniRef90_Q9BZQ8
UniRef50:
UniRef50_Q9BZQ8
UniGene:
Hs.518662
CCDS:
CCDS1364.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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