| Type | Description |
|---|---|
| Definition | alkaline phosphatase 3, intestine, not Mn requiring |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 11:05:00 | data do not support a functional role of AKP3 in adipose tissue development, or insulin sensitivity | 30064292 |
| 2019-01-12 10:56:00 | intestinal Akp3 deletion affects Na+-dependent Pi transport in the small intestine. In the adenine-induced renal failure model, Akp3 is predicted to be a factor contributing to suppression of the plasma Pi concentration. | 30212831 |
| 2015-02-28 10:24:00 | Authors found that Akp3(-/-) mice acquired lipopolysaccharide tolerance during postweaning development, suggesting that Akp3 plays an important role in immune education. | 25348635 |
| 2013-06-29 11:28:00 | Intestinal alkaline phosphatase prevents metabolic syndrome in mice. | 23569246 |
| 2011-06-25 14:41:00 | These data suggest that IAP is a local immunomodulating factor, perhaps regulating LPS-toll-like receptor 4 (TLR4) interaction between commensal microflora and intestinal epithelium. | 20844955 |
| Type | IDs |
|---|---|
| Synonymous | Akp-3, IAP, dIAP |
| Gene |
UniProtKB-ID:
Q1LZM2_MOUSE,
F8VQM0_MOUSE
UniprotKB:
Q1LZM2,
F8VQM0
UniParc:
UPI0000D63F6F,
UPI00005645E6
EMBL:
BC115745,
AC102611
Ensembl:
ENSMUSG00000036500
KO:
mmu:11648
|
| Nucleutide sequences |
EMBL-CDS:
AAI15746.1
Ensembl_TRS:
ENSMUST00000044878
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037497
RefSeq:
NP_031458.2
|
| Others |
UniRef100:
UniRef100_F8VQM0,
UniRef100_Q1LZM2
UniRef90:
UniRef90_P24822
UniRef50:
UniRef50_P09923
UniGene:
Mm.377076
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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